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Peyer's patches (PP) comprise transmucosal clusters of lymphoid follicles overlaid with a specialized lympho-epithelium and consequently play a central role in the induction of mucosal immune responses in the gut. Despite considerable achievements in the last 3 decades, in our understanding of how PP are involved in the induction of immune responses, much remains to be learned about these major organized lymphoid organs. The history and current status of PP termed 'the major inductive site of immune responses' is reviewed. The present understanding of PP biology and function, taking into account their preferential and unique retention of immune competent cells at specific sites, is discussed.
L H C Makala, and
N Suzuki, and
H Nagasawa
May 2000,
Journal of immunology (Baltimore, Md. : 1950),
L H C Makala, and
N Suzuki, and
H Nagasawa
February 2008,
Gastroenterology,
L H C Makala, and
N Suzuki, and
H Nagasawa
September 2010,
International journal of inflammation,
L H C Makala, and
N Suzuki, and
H Nagasawa
January 1997,
Research in immunology,
L H C Makala, and
N Suzuki, and
H Nagasawa
April 2001,
European journal of immunology,
L H C Makala, and
N Suzuki, and
H Nagasawa
October 1995,
Veterinary immunology and immunopathology,
L H C Makala, and
N Suzuki, and
H Nagasawa
July 1996,
Fiziologicheskii zhurnal imeni I.M. Sechenova,
L H C Makala, and
N Suzuki, and
H Nagasawa
January 1996,
International review of cytology,
L H C Makala, and
N Suzuki, and
H Nagasawa
May 2001,
Trends in immunology,
L H C Makala, and
N Suzuki, and
H Nagasawa
November 2019,
Georgian medical news,
