BIOMAT Database Logo BIOMAT Database Logo

Synthesis and insecticidal evaluation of novel N-(S-amino)sulfenylated derivatives of diacylhydrazines. 2002

Qingmin Wang, and Junran Cheng, and Runqin Huang
Research Institute of Elemento-Organic Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, People's Republic of China. wang98h@263.net

A series of new N-(S-amino)sulfenylated derivatives of diacylhydrazines were synthesized by the reaction of S-aminosulfenyl chlorides with N-tert-butyl-N'-benzoyl-N-substituted benzoylhydrazines in the presence of sodium hydride, and evaluated for moulting hormone mimicking activity. In the course of syntheses, N-N bond cleavage in diacylhydrazines was found and the reaction was studied in some detail. The results of bioassay showed that the title compounds exhibit excellent larvicidal activity. Toxicity assays indicated that these compounds can induce a premature, abnormal and lethal larval mount.

UI MeSH Term Description Entries
D007306 Insecticides Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics. Insecticide
D007313 Insecta Members of the phylum ARTHROPODA composed or organisms characterized by division into three parts: head, thorax, and abdomen. They are the dominant group of animals on earth with several hundred thousand different kinds. Three orders, HEMIPTERA; DIPTERA; and SIPHONAPTERA; are of medical interest in that they cause disease in humans and animals. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p1). Insects,Insect
D007814 Larva Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals. Maggots,Tadpoles,Larvae,Maggot,Tadpole
D009682 Magnetic Resonance Spectroscopy Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING). In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D006834 Hydrazines Substituted derivatives of hydrazine (formula H2N-NH2). Hydrazide
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001549 Benzamides BENZOIC ACID amides.
D001681 Biological Assay A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc. Bioassay,Assay, Biological,Assays, Biological,Biologic Assay,Biologic Assays,Assay, Biologic,Assays, Biologic,Bioassays,Biological Assays
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular

Related Publications

Qingmin Wang, and Junran Cheng, and Runqin Huang
Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 1. N-alkoxysulfenate derivatives.
November 2007, Journal of agricultural and food chemistry,
Qingmin Wang, and Junran Cheng, and Runqin Huang
Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 2. N-substituted phenoxysulfenate derivatives.
July 2008, Journal of agricultural and food chemistry,
Qingmin Wang, and Junran Cheng, and Runqin Huang
Synthesis and insecticidal activities of novel N-sulfenyl-N'-tert-butyl-N,N'-diacylhydrazines. 3. N-(alkyldithio), n-(aminothio), and N,N-dithio derivatives.
November 2008, Journal of agricultural and food chemistry,
Qingmin Wang, and Junran Cheng, and Runqin Huang
Selective toxicity of N-sulfenylated derivatives of insecticidal methylcarbamate esters.
January 1973, Journal of agricultural and food chemistry,
Qingmin Wang, and Junran Cheng, and Runqin Huang
Synthesis and insecticidal evaluation of novel N-oxalyl derivatives of tebufenozide.
November 2004, Journal of agricultural and food chemistry,
Qingmin Wang, and Junran Cheng, and Runqin Huang
Synthesis and insecticidal activity of N-tert-butyl-N,N'-diacylhydrazines containing 1,2,3-thiadiazoles.
January 2011, Journal of agricultural and food chemistry,
Qingmin Wang, and Junran Cheng, and Runqin Huang
Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines.
February 2010, Journal of agricultural and food chemistry,
Qingmin Wang, and Junran Cheng, and Runqin Huang
Synthesis and insecticidal evaluation of novel N'-tert-butyl-N'-substitutedbenzoyl-N-5-chloro-6-chromanecarbohydrazide derivatives.
January 2008, Bioorganic & medicinal chemistry,
Qingmin Wang, and Junran Cheng, and Runqin Huang
Design, synthesis and antifungal/insecticidal evaluation of novel cinnamide derivatives.
October 2011, Molecules (Basel, Switzerland),
Qingmin Wang, and Junran Cheng, and Runqin Huang
Design, synthesis, and evaluation of novel arecoline-linked amino acid derivatives for insecticidal and antifungal activities.
April 2024, Scientific reports,
Copied contents to your clipboard!