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[Effect of hepatic arterial infusion chemotherapy for liver metastasis from gastric cancer]. 2002
Ryoichi Shizawa, and
Yutaka Nagahori, and
Nobufumi Kumamoto, and
Harumi Yamamoto, and
Kazunaga Takeda, and
Youhei Hamaguchi, and
Tadao Fukushima, and
Masayoshi Yamamoto, and
Masatoshi Mogaki, and
Shingo Fukasawa, and
Kazuya Eguchi, and
Masaki Kawahara, and
Kaoru Nagahori, and
Hideo Hosoi, and
Takeshi Ohara
Dept. of Surgery, Yokosuka Kyousai Hospital.
We performed hepatic arterial infusion (HAI) chemotherapy for 4 patients with advanced gastric cancer who had undergone curative resection except for liver metastasis. The main antineoplastic drugs were 5-fluorouracil (5-FU), mitomycin C (MMC) and cisplatin (CDDP). A catheter was inserted into the hepatic artery by interventional radiological techniques in 3 patients and operatively in 1 patient. The response rate for 4 patients was 75% (CR2, PR1, PD1). The adverse events were Grade 3/4 nausea and/or vomiting in 2 cases. The HAI chemotherapy was effective and useful for patients with advanced gastric cancer who had no unresectable lesions except for liver metastasis.
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