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Using dinitrochlorbenzene contact-sensitized guinea pigs, several DNP conjugates have been assayed in the direct macrophage migration inhibition test (MMIT). Although no significant differences could be observed between the carriers used, conjugates prepared from serum proteins and epidermal extracts tended to give the strongest inhibition of macrophage migration. Conjugates prepared from cells cultured in vitro in the presence of hapten did not cause more inhibition than control conjugates prepared in the absence of cell metabolism. The direct MMIT showed statistical differences between sensitized and nonsensitized groups of guinea pigs. However, none of the conjugates permitted conclusions to be drawn with regard to individual animals.
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
January 1978,
International archives of allergy and applied immunology,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
July 1981,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
February 1974,
Cellular immunology,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
February 1976,
Cellular immunology,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
May 1972,
Experientia,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
February 1978,
The Journal of investigative dermatology,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
January 1969,
International archives of allergy and applied immunology,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
May 1971,
Clinical and experimental immunology,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
January 1985,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
M von Blomberg, and
U Rijlaarsdam, and
R J Scheper
September 1973,
Immunology,
