Analysis of pulpal reactions to restorative procedures, materials, pulp capping, and future therapies. 2002

Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
Department of Oral Biology, Indiana University School of Dentistry, 1121 West Michigan Street, Indianapolis, IN 46202-5186, USA. petmurra@iupui.edu

Every year, despite the effectiveness of preventive dentistry and dental health care, 290 million fillings are placed each year in the United States; two-thirds of these involve the replacement of failed restorations. Improvements in the success of restorative treatments may be possible if caries management strategies, selection of restorative materials, and their proper use to avoid post-operative complications were investigated from a biological perspective. Consequently, this review will examine pulp injury and healing reactions to different restorative variables. The application of tissue engineering approaches to restorative dentistry will require the transplantation, replacement, or regeneration of cells, and/or stimulation of mineralized tissue formation. This might solve major dental problems, by remineralizing caries lesions, vaccinating against caries and oral diseases, and restoring injured or replacing lost teeth. However, until these therapies can be introduced clinically, the avoidance of post-operative complications with conventional therapies requires attention to numerous aspects of treatment highlighted in this review.

UI MeSH Term Description Entries
D009059 Mouth Diseases Diseases involving the MOUTH. Disease, Mouth,Diseases, Mouth,Mouth Disease
D011671 Pulpitis Inflammation of the DENTAL PULP, usually due to bacterial infection in dental caries, tooth fracture, or other conditions causing exposure of the pulp to bacterial invasion. Chemical irritants, thermal factors, hyperemic changes, and other factors may also cause pulpitis. Inflammation, Endodontic,Endodontic Inflammation,Endodontic Inflammations,Inflammations, Endodontic,Pulpitides
D012038 Regeneration The physiological renewal, repair, or replacement of tissue. Endogenous Regeneration,Regeneration, Endogenous,Regenerations
D003731 Dental Caries Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp. Caries, Dental,Carious Lesions,Dental Cavities,Dental Cavity,Dental Decay,Dental White Spots,Carious Dentin,Decay, Dental,Dental White Spot,White Spot, Dental,White Spots, Dental,Carious Dentins,Carious Lesion,Cavities, Dental,Cavity, Dental,Dentin, Carious,Dentins, Carious,Lesion, Carious,Lesions, Carious,Spot, Dental White,Spots, Dental White
D003737 Dental Cavity Preparation An operation in which carious material is removed from teeth and biomechanically correct forms are established in the teeth to receive and retain restorations. A constant requirement is provision for prevention of failure of the restoration through recurrence of decay or inadequate resistance to applied stresses. (Boucher's Clinical Dental Terminology, 4th ed, p239-40) Cavity Preparation, Dental,Cavity Preparations, Dental,Dental Cavity Preparations,Preparation, Dental Cavity,Preparations, Dental Cavity
D003763 Dental Leakage The seepage of fluids, debris, and micro-organisms between the walls of a prepared dental cavity and the restoration. Dental Leakages,Leakage, Dental,Leakages, Dental
D003764 Dental Materials Materials used in the production of dental bases, restorations, impressions, prostheses, etc. Dental Material,Material, Dental,Materials, Dental
D003782 Dental Pulp A richly vascularized and innervated connective tissue of mesodermal origin, contained in the central cavity of a tooth and delimited by the dentin, and having formative, nutritive, sensory, and protective functions. (Jablonski, Dictionary of Dentistry, 1992) Dental Pulps,Pulp, Dental,Pulps, Dental
D003785 Dental Pulp Capping Application of a protective agent to an exposed pulp (direct capping) or the remaining thin layer of dentin over a nearly exposed pulp (indirect capping) in order to allow the pulp to recover and maintain its normal vitality and function. Pulp Capping,Capping, Dental Pulp,Capping, Pulp,Pulp Capping, Dental,Cappings, Dental Pulp,Cappings, Pulp,Dental Pulp Cappings,Pulp Cappings,Pulp Cappings, Dental
D003789 Dental Pulp Exposure The result of pathological changes in the hard tissue of a tooth caused by carious lesions, mechanical factors, or trauma, which render the pulp susceptible to bacterial invasion from the external environment. Exposure, Dental Pulp,Pulp Exposure, Dental

Related Publications

Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
June 1967, Shigaku = Odontology; journal of Nihon Dental College,
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
June 2000, Journal of oral science,
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
June 1992, Current opinion in dentistry,
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
January 1979, Clinical preventive dentistry,
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
April 1986, Scandinavian journal of dental research,
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
July 1967, Journal of the American Dental Association (1939),
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
April 2011, Journal of endodontics,
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
June 1975, Journal of dental research,
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
January 2023, Clinical, cosmetic and investigational dentistry,
Peter E Murray, and L Jack Windsor, and Thomas W Smyth, and Abeer A Hafez, and Charles F Cox
July 1969, Oral surgery, oral medicine, and oral pathology,
Copied contents to your clipboard!