-transparent.png){kind=logo}
From 1953 to 1972, approximately 170 patients less than 16 years old were seen at the Mayo Clinic for isolated secundum atrial septal defect. Thirteen of these patients were initially seen when they were less than 2 years old. Eleven of the patients had symptoms, and one of these died. Four patients failed to respond to medical management and underwent successful repair of their defects before they were 2 years old. Infants with isolated secundum atrial septal defect and significant symptoms are at an increased risk of death. Consideration should be given to early surgical closure of the defect in those infants who do not respond promptly and completely to medical therapy. Surgical repair in infancy can be accomplished with minimal risk and excellent early and long-term clinical results.
J G Spangler, and
R H Feldt, and
G K Danielson
October 1981,
Archives of disease in childhood,
J G Spangler, and
R H Feldt, and
G K Danielson
June 2005,
The Journal of thoracic and cardiovascular surgery,
J G Spangler, and
R H Feldt, and
G K Danielson
June 1986,
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai,
J G Spangler, and
R H Feldt, and
G K Danielson
August 2018,
QJM : monthly journal of the Association of Physicians,
J G Spangler, and
R H Feldt, and
G K Danielson
March 2009,
Journal of the American College of Cardiology,
J G Spangler, and
R H Feldt, and
G K Danielson
November 1976,
The Journal of thoracic and cardiovascular surgery,
J G Spangler, and
R H Feldt, and
G K Danielson
December 1965,
Circulation,
J G Spangler, and
R H Feldt, and
G K Danielson
July 1994,
Postgraduate medical journal,
J G Spangler, and
R H Feldt, and
G K Danielson
January 1990,
Kokyu to junkan. Respiration & circulation,
J G Spangler, and
R H Feldt, and
G K Danielson
January 2014,
European heart journal. Cardiovascular Imaging,
