Biomaterial Database

[Duspatalin in functional disorders of the Oddi's sphincter in patients subjected cholecystectomy]. 2002

A A Il'chenko, and E V Bystrovskaia

Central Scientific Research Institute of Gastroenterology, Moscow.

There was an examination of 20 patients who had cholecystectomy and have dysfunctional disorders of the Oddi's sphincter. All of the patients underwent the monotherapy with Mebeverine Retard in the dosage of 200 mg twice a day. The treatment efficiency was evaluated by the dynamics of clinical symptoms, results of the study of biochemical blood indices, data of the ultrasonic examination, and intragastric pH measurement. A positive dynamics was observed against the background of the preparation administration, and it became apparent from the disappearance or reduction of pains strength, dyspeptic manifestations, normalization or improvement of biochemical blood indices, and reduction of the common bile duct lumen width according to the ultrasonic examination data.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009803	Sphincter of Oddi	The sphincter of the hepatopancreatic ampulla within the duodenal papilla. The COMMON BILE DUCT and main pancreatic duct pass through this sphincter.	Oddi's Sphincter,Oddi Sphincter,Oddis Sphincter,Sphincter, Oddi's
D010276	Parasympatholytics	Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS.	Antispasmodic,Antispasmodic Agent,Antispasmodic Drug,Antispasmodics,Parasympathetic-Blocking Agent,Parasympathetic-Blocking Agents,Parasympatholytic,Parasympatholytic Agent,Parasympatholytic Drug,Spasmolytic,Spasmolytics,Antispasmodic Agents,Antispasmodic Drugs,Antispasmodic Effect,Antispasmodic Effects,Parasympatholytic Agents,Parasympatholytic Drugs,Parasympatholytic Effect,Parasympatholytic Effects,Agent, Antispasmodic,Agent, Parasympathetic-Blocking,Agent, Parasympatholytic,Agents, Antispasmodic,Agents, Parasympathetic-Blocking,Agents, Parasympatholytic,Drug, Antispasmodic,Drug, Parasympatholytic,Drugs, Antispasmodic,Drugs, Parasympatholytic,Effect, Antispasmodic,Effect, Parasympatholytic,Effects, Antispasmodic,Effects, Parasympatholytic,Parasympathetic Blocking Agent,Parasympathetic Blocking Agents
D010627	Phenethylamines	A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed)	Phenylethylamines
D002763	Cholecystectomy	Surgical removal of the GALLBLADDER.	Cholecystectomies
D002769	Cholelithiasis	Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).	Gallstone Disease,Cholelithiases,Gallstone Diseases
D003137	Common Bile Duct Diseases	Diseases of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man