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Genetic linkage between the HL-A and Bf loci could be confirmed in 43 families with 168 offspring. In 4 families, 5 recombinants out of 82 informative meiotic divisions were observed (r = 6.1%). The localisation of the Bf marker system was studied in 3 families with crossovers between HL-A and MLC. From these data the following map order of human chromosome 6 can be proposed: HL-A (1st locus) -- HL-A (2nd locus)--MLC-Bf---PGM(3). The fact that important components of the classical and alternate pathway of complement activation are governed by genes closely linked with HL-A and MLC loci leads to the proposition to include the Bf system into the Major Histocompatibility Complex in man.
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
July 1983,
American journal of human genetics,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
January 1977,
Scandinavian journal of immunology,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
January 1984,
Human heredity,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
January 1977,
Vox sanguinis,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
December 1975,
Humangenetik,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
January 1982,
Human heredity,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
September 1976,
Revue francaise de transfusion et immuno-hematologie,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
January 1983,
Human genetics,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
January 1983,
Acta endocrinologica,
C Rittner, and
H Grosse-Wilde, and
B Netzel, and
S Scholz, and
H Lorenz, and
E D Albert
November 1981,
Transplantation,
