Biomaterial Database

[The actions of glucocorticoid receptor and 11 beta-hydroxysteroid dehydrogenases in the brain]. 2001

S L Wan, and J J Xu, and G Sun

UI	MeSH Term	Description	Entries
D011965	Receptors, Glucocorticoid	Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.	Corticoid Type II Receptor,Glucocorticoid Receptors,Glucocorticoids Receptor,Corticoid II Receptor,Corticoid Type II Receptors,Glucocorticoid Receptor,Receptors, Corticoid II,Receptors, Corticoid Type II,Receptors, Glucocorticoids,Corticoid II Receptors,Glucocorticoids Receptors,Receptor, Corticoid II,Receptor, Glucocorticoid,Receptor, Glucocorticoids
D001921	Brain	The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.	Encephalon
D003345	Corticosterone	An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006913	Hydroxysteroid Dehydrogenases	Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-.	Hydroxysteroid Dehydrogenase,Dehydrogenase, Hydroxysteroid,Dehydrogenases, Hydroxysteroid
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D042842	11-beta-Hydroxysteroid Dehydrogenases	Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors.	11 beta-Hydroxysteroid Dehydrogenase,11-Hydroxysteroid Dehydrogenase,11B-Hydroxysteroid Dehydrogenase,11beta-Hydroxysteroid Dehydrogenase,Corticosteroid 11-Oxidoreductase,Corticosteroid 11-Reductase,Cortisone 11-Oxoreductase,11 Hydroxysteroid Dehydrogenase,11 beta Hydroxysteroid Dehydrogenase,11 beta Hydroxysteroid Dehydrogenases,11-Oxidoreductase, Corticosteroid,11-Oxoreductase, Cortisone,11-Reductase, Corticosteroid,11B Hydroxysteroid Dehydrogenase,11beta Hydroxysteroid Dehydrogenase,Corticosteroid 11 Oxidoreductase,Corticosteroid 11 Reductase,Cortisone 11 Oxoreductase,Dehydrogenase, 11 beta-Hydroxysteroid,Dehydrogenase, 11-Hydroxysteroid,Dehydrogenase, 11B-Hydroxysteroid,Dehydrogenase, 11beta-Hydroxysteroid,Dehydrogenases, 11-beta-Hydroxysteroid,beta-Hydroxysteroid Dehydrogenase, 11