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[Studies of the chemical constituents of Swertia davida Franch]. 2002

Gui-shan Tan, and Kang-ping Xu, and Ping-sheng Xu, and Gao-yun Hu, and Yuan-jian Li
Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China.

OBJECTIVE To study the active constituents of Swertia davidi Franch.. METHODS Chromatography was used to isolate and purify the chemical components, their structures were identified by spectral analysis. RESULTS Three compounds were identified as 1,7-dihydroxy-3,8-dimethoxyxanthone (gentiacaulein) (V), 1,8-dihydroxy-3,7-dimethoxyxanthone (methylswertianin) (VI) and 1,8-dihydroxy-3,4,7-trimethoxyxanthone (VII). CONCLUSIONS Compound VII is a novel xanthone, named daviditin A, the others were isolated from Swertia davidi Franch. for the first time.

UI MeSH Term Description Entries
D010946 Plants, Medicinal Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals. Herbs, Medicinal,Medicinal Herbs,Healing Plants,Medicinal Plants,Pharmaceutical Plants,Healing Plant,Herb, Medicinal,Medicinal Herb,Medicinal Plant,Pharmaceutical Plant,Plant, Healing,Plant, Medicinal,Plant, Pharmaceutical,Plants, Healing,Plants, Pharmaceutical
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D044004 Xanthones A group of XANTHENES that contain a 9-keto OXYGEN. Xanthone Derivatives,Derivatives, Xanthone
D029967 Swertia A plant genus of the family GENTIANACEAE. It is a source of swertiapuniside and IRIDOID GLYCOSIDES. Swertia chirata,Swertia chirayita,Swertias

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