-transparent.png){kind=logo}
Changes induced in left ventricular (LV) hemodynamics by isometric exercise were analyzed in 43 patients: 30 with coronary heart disease (CAD), four with noncoronary heart disease, nine normal. Volumes were angiographically determined and correlated with left ventricular end-diastolic pressure (LVEDP) both at rest and during the fifth minute of 30% sustained handgrip (HNG). All normals and eight with CAD improved LV function during HNG. LVEDP decreased or remained constant, end-diastolic volume (EDV) decreased, end-systolic volume (ESV) decreased, as ejection fraction (EF) remained constant. None of these eight CAD cases altered their regional LV contraction pattern during HNG. Twenty-five patients, 21 CAD and four nonCAD, showed diminished LV function during HNG. LVEDP increased, EDV decreased, ESV increased, as EF declined. In these 21 CAD patients, at least one major coronary vessel was narrowed 70% or more and, with but two exceptions, was not supported by adequate collaterals. In 18, new asynergic zones developed in previously normally contracting areas or pre-existing asynergic zones extended during HNG.
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
June 2009,
Internal and emergency medicine,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
February 1965,
Clinical science,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
April 1979,
Circulation,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
April 1979,
Fortschritte der Medizin,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
January 1981,
Clinical cardiology,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
October 1962,
American heart journal,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
August 1975,
The American journal of cardiology,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
June 1981,
Computertomographie,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
February 1987,
Clinical cardiology,
A P Flessas, and
G P Connelly, and
S Handa, and
C R Tilney, and
C K Kloster, and
R H Rimmer, and
J F Keefe, and
M D Klein, and
T J Ryan
March 1981,
Vnitrni lekarstvi,
