Intracellular analysis of directional sensitivity of tectal neurons of the frog. 2003

Noriaki Hoshino, and Nobuyoshi Matsumoto
Kyushu Institute of Technology, Faculty of Computer Science and Systems Engineering, Department of Biophysical Engineering and Science, Iizuka, 820-8502, Fukuoka, Japan.

The directional sensitivity of tectal neurons of the frog was examined by means of in vivo whole cell recording technique. Three kinds of stimulus were applied; (1) diffuse light 'on-off', (2) moving dark spot and (3) light spot given at one dimensional grid points. The first stimulus revealed whether or not retinal 'on-off' (R3) or 'off' (R4) fibers contribute to the response. As reported earlier, the following patterns were found for both light 'on' and light 'off': EPSPs only, IPSPs only or a combination of EPSPs and IPSPs. Four directionally sensitive neurons and three non-directionally sensitive neurons were found using the second stimulus. Using the third stimulus, responses at up to 11 positions separated by 2 degrees or 4 degrees were recorded. By measuring the amplitudes of 'on' and 'off' responses at different times, spatio-temporal receptive fields were composed. Two types of directional sensitivity were found. The response of the first type was composed of exclusively excitatory potentials, but the second type was composed of a combination of excitatory and inhibitory potentials. The spatio-temporal receptive field of the second type showed spatially separated excitatory and inhibitory regions with constant latencies. Such simple spatio-temporal receptive field organization was not found for directional sensitive neurons of the cat visual cortex. The spatio-temporal receptive field organization of the second type of directionally sensitive neuron in the present study is in agreement with striated receptive field found in some of the T5 neurons classified by extracellular unit recording [Frog Neurobiology (1976) 297].

UI MeSH Term Description Entries
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D008297 Male Males
D008954 Models, Biological Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment. Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D009068 Movement The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior. Movements
D009433 Neural Inhibition The function of opposing or restraining the excitation of neurons or their target excitable cells. Inhibition, Neural
D009474 Neurons The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM. Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D010775 Photic Stimulation Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity. Stimulation, Photic,Visual Stimulation,Photic Stimulations,Stimulation, Visual,Stimulations, Photic,Stimulations, Visual,Visual Stimulations
D011892 Rana catesbeiana A species of the family Ranidae (true frogs). The only anuran properly referred to by the common name "bullfrog", it is the largest native anuran in North America. Bullfrog,Bullfrogs,Rana catesbeianas,catesbeiana, Rana
D011930 Reaction Time The time from the onset of a stimulus until a response is observed. Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D005260 Female Females

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