BIOMAT Database Logo BIOMAT Database Logo

Molecular typing of exfoliative toxin-producing Staphylococcus aureus strains involved in epidermolytic infections. 2003

Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
Department of Genetics and Molecular Biology, Faculty of Science, Masaryk University, Brno, Czech Republic. vladkar@sci.muni.cz

Genotyping of sixteen exfoliative toxin-producing (ET-positive) strains of Staphylococcus aureus isolated in maternity units of two distant hospitals was accomplished by PFGE, ribotyping, PCR ribotyping, and prophage carriage. Three strains secreted combined ETA + ETB, and the remaining produced ETA and enterotoxin C, or TSST-1. The comparison of various genomic profiles resulted in the identification of nine genotypes. The presence of one prevailing genotype was demonstrated in each hospital. Evidence was given that the outbreak-related ET-positive strains causing the skin disease pemphigus neonatorum disseminated in both the hospitals did not originate from a single source or a common ancestor.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D001768 Blister Visible accumulations of fluid within or beneath the epidermis. Bulla,Vesication,Bleb,Bullae,Bullous Lesion,Blebs,Blisters,Bullous Lesions,Lesion, Bullous,Lesions, Bullous,Vesications
D003428 Cross Infection Any infection which a patient contracts in a health-care institution. Hospital Infections,Nosocomial Infections,Health Care Associated Infection,Health Care Associated Infections,Healthcare Associated Infections,Infection, Cross,Infections, Hospital,Infections, Nosocomial,Cross Infections,Healthcare Associated Infection,Hospital Infection,Infection, Healthcare Associated,Infection, Hospital,Infection, Nosocomial,Infections, Cross,Infections, Healthcare Associated,Nosocomial Infection
D004196 Disease Outbreaks Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS. Outbreaks,Infectious Disease Outbreaks,Disease Outbreak,Disease Outbreak, Infectious,Disease Outbreaks, Infectious,Infectious Disease Outbreak,Outbreak, Disease,Outbreak, Infectious Disease,Outbreaks, Disease,Outbreaks, Infectious Disease
D005083 Exfoliatins Protein exotoxins from Staphylococcus aureus, phage type II, which cause epidermal necrolysis. They are proteins with a molecular weight of 26,000 to 32,000. They cause a condition variously called scaled skin, Lyell or Ritter syndrome, epidermal exfoliative disease, toxic epidermal necrolysis, etc. Dermolysins,Epidermolysins,Epidermolytic Toxins,Exfoliative Toxins,Exfoliatin Toxin A,Exfoliative Toxin B,Staphylococcal Exfoliative Toxin,Exfoliative Toxin, Staphylococcal,Toxin A, Exfoliatin,Toxin B, Exfoliative,Toxin, Staphylococcal Exfoliative,Toxins, Epidermolytic,Toxins, Exfoliative
D005260 Female Females
D005838 Genotype The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS. Genogroup,Genogroups,Genotypes
D006771 Hospitals, Maternity Special hospitals which provide care to women during pregnancy and parturition. Maternity Hospitals,Hospital, Maternity,Maternity Hospital
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
[The search for strains of Staphylococcus aureus producing exfoliative toxin].
January 1988, Revista latinoamericana de microbiologia,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
Isolation of exfoliative toxin-producing Staphylococcus aureus.
October 2003, The Pediatric infectious disease journal,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
Epidemiological investigation of exfoliative toxin-producing Staphylococcus aureus strains in hospitalized patients.
March 1984, Journal of clinical microbiology,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
Microbiologic characteristics of exfoliative toxin-producing Staphylococcus aureus.
May 1988, The Pediatric infectious disease journal,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
The epidermolytic (exfoliative) toxins of Staphylococcus aureus.
August 1995, Medical microbiology and immunology,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
Recombinant epidermolytic (exfoliative) toxin A of Staphylococcus aureus is not a superantigen.
January 1992, Medical microbiology and immunology,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
A double outbreak of exfoliative toxin-producing strains of Staphylococcus aureus in a maternity unit.
February 1994, Epidemiology and infection,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
Nasal, axillary, and perineal carriage of Staphylococcus aureus among women: identification of strains producing epidermolytic toxin.
August 1991, Journal of clinical pathology,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
Plasmids in epidermolytic strains of Staphylococcus aureus.
May 1981, Journal of general microbiology,
Vladislava Růzicková, and Roman Pantůcek, and Petr Petrás, and Jirí Doskar, and Ivo Sedlácek, and Stanislav Rosypal
Purification of epidermolytic toxin of Staphylococcus aureus.
January 1988, Methods in enzymology,
Copied contents to your clipboard!