Biomaterial Database

Organic solvents permeation through protective nitrile gloves. 2003

Keh-Ping Chao, and Pak-Hing Lee, and Min-Jet Wu

Department of Occupational Safety and Health, Institute of Environmental Health, China Medical College, 91 Hsueh-Shin Road, Taichung, Taiwan, ROC. kpchao@mail.cmc.edu.tw

Effective diffusion coefficients for the permeation of several organic solvents through nitrile gloves were experimentally investigated using the American Society for Testing and Materials (ASTM) F-739 test cell method. Fick's effective diffusion coefficients for benzene, toluene, ethyl benzene, xylene, and styrene were estimated to be 0.61+/-0.02, 0.50+/-0.06, 0.27+/-0.02, 0.31+/-0.03, and 0.21+/-0.03 (x10(-6)cm(2)/s), respectively. These results were comparable to results found by others using different permeation models. Using a transient mass diffusion equation and appropriate initial and boundary conditions, the effective diffusion coefficients were found to adequately simulate the concentration profiles of the organic solvents in the collection chamber during the permeation test. The effective diffusion coefficients were found to be inversely correlated to the molecular weight of the compounds. The results of this study can be used to estimate the exposure to workers using nitrile gloves.

UI	MeSH Term	Description	Entries
D008422	Materials Testing	The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.	Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D008962	Models, Theoretical	Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.	Experimental Model,Experimental Models,Mathematical Model,Model, Experimental,Models (Theoretical),Models, Experimental,Models, Theoretic,Theoretical Study,Mathematical Models,Model (Theoretical),Model, Mathematical,Model, Theoretical,Models, Mathematical,Studies, Theoretical,Study, Theoretical,Theoretical Model,Theoretical Models,Theoretical Studies
D009570	Nitriles	Organic compounds containing the -CN radical. The concept is distinguished from CYANIDES, which denotes inorganic salts of HYDROGEN CYANIDE.	Nitrile
D009930	Organic Chemicals	A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.	Organic Chemical,Chemical, Organic,Chemicals, Organic
D010539	Permeability	Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions.	Permeabilities
D004058	Diffusion	The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.	Diffusions
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012997	Solvents	Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar. (Grant & Hackh's Chemical Dictionary, 5th ed)	Solvent
D016273	Occupational Exposure	The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.	Exposure, Occupational,Exposures, Occupational,Occupational Exposures
D017575	Gloves, Protective	Covering for the hands usually with separation for the fingers, made of various materials for protection against infections, toxic substances, extremes of hot and cold, radiation, water immersion, etc. Protective gloves may be worn by patients, care givers, laboratory personnel, industrial workers, and police, among others.	Protective Gloves