Primary epithelioid hemangioendothelioma originating in the lower petroclival region: case report. 2003

Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
Department of Neurosurgery, Gunma University School of Medicine, Maebashi, Gunma, Japan.

BACKGROUND We report the first case of primary epithelioid hemangioendothelioma (EH) originating in the lower petroclival region. METHODS A 55-year-old female presented with a 45-year history of subclinical atrophy on the right side of her tongue and a 15-year history of hoarseness. Neuroimaging revealed an expansile, homogeneously enhanced intraosseous mass with bony shell and honeycomb configuration in the petroclival region. A right far lateral transcondylar approach was utilized for subtotal removal of the tumor, which demonstrated high vascularity in the petroclival bone. Histopathological and immunohistochemical examination confirmed the diagnosis of EH. Because of the intermediate malignancy, adjuvant gamma knife radiotherapy was performed for the residual mass 5 months after surgery. CONCLUSIONS EH rarely occurs in the skull base region. The appearance of surrounding bony structure and rich vascularity are important findings for the differential diagnosis. A far lateral transcondylar approach provides sufficient exposure of the jugular tubercle and lower clivus. Additional radiotherapy may be recommended for residual tumors with a high MIB-1 labeling index.

UI MeSH Term Description Entries
D007150 Immunohistochemistry Histochemical localization of immunoreactive substances using labeled antibodies as reagents. Immunocytochemistry,Immunogold Techniques,Immunogold-Silver Techniques,Immunohistocytochemistry,Immunolabeling Techniques,Immunogold Technics,Immunogold-Silver Technics,Immunolabeling Technics,Immunogold Silver Technics,Immunogold Silver Techniques,Immunogold Technic,Immunogold Technique,Immunogold-Silver Technic,Immunogold-Silver Technique,Immunolabeling Technic,Immunolabeling Technique,Technic, Immunogold,Technic, Immunogold-Silver,Technic, Immunolabeling,Technics, Immunogold,Technics, Immunogold-Silver,Technics, Immunolabeling,Technique, Immunogold,Technique, Immunogold-Silver,Technique, Immunolabeling,Techniques, Immunogold,Techniques, Immunogold-Silver,Techniques, Immunolabeling
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D016634 Radiosurgery A radiological stereotactic technique developed for cutting or destroying tissue by high doses of radiation in place of surgical incisions. It was originally developed for neurosurgery on structures in the brain and its use gradually spread to radiation surgery on extracranial structures as well. The usual rigid needles or probes of stereotactic surgery are replaced with beams of ionizing radiation directed toward a target so as to achieve local tissue destruction. Gamma Knife Radiosurgery,Linear Accelerator Radiosurgery,Stereotactic Body Radiotherapy,Stereotactic Radiosurgery,CyberKnife Radiosurgery,LINAC Radiosurgery,Radiosurgery, Gamma Knife,Radiosurgery, Linear Accelerator,Radiosurgery, Stereotactic,Stereotactic Radiation,Stereotactic Radiation Therapy,CyberKnife Radiosurgeries,Gamma Knife Radiosurgeries,LINAC Radiosurgeries,Linear Accelerator Radiosurgeries,Radiation Therapy, Stereotactic,Radiation, Stereotactic,Radiosurgery, CyberKnife,Radiosurgery, LINAC,Radiotherapy, Stereotactic Body,Stereotactic Body Radiotherapies,Stereotactic Radiation Therapies,Stereotactic Radiations,Stereotactic Radiosurgeries,Therapy, Stereotactic Radiation
D018323 Hemangioendothelioma, Epithelioid A tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. These tumors are thought to have "borderline" aggression, where one-third develop local recurrences, but only rarely metastasize. It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (Segen, Dictionary of Modern Medicine, 1992) Epithelioid Hemangioendothelioma,Epithelioid Hemangioendotheliomas,Hemangioendotheliomas, Epithelioid
D018365 Neoplasm, Residual Remnant of a tumor or cancer after primary, potentially curative therapy. Minimal Residual Disease,Residual Cancer,Residual Tumor,Minimal Disease, Residual,Residual Disease, Minimal,Residual Neoplasm,Residual Tumour,Cancer, Residual,Minimal Residual Diseases,Residual Cancers,Residual Minimal Disease,Residual Minimal Diseases,Residual Neoplasms,Residual Tumors,Residual Tumours,Tumour, Residual
D019292 Skull Base Neoplasms Neoplasms of the base of the skull specifically, differentiated from neoplasms of unspecified sites or bones of the skull (SKULL NEOPLASMS). Neoplasms, Skull Base,Neoplasm, Skull Base,Skull Base Neoplasm

Related Publications

Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
September 1999, Changgeng yi xue za zhi,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
May 2004, Journal of neuro-oncology,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
October 2011, Neuropathology : official journal of the Japanese Society of Neuropathology,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
July 2012, Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
January 2022, Open respiratory archives,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
November 2022, Oncology letters,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
January 1989, Skeletal radiology,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
October 2012, Surgery today,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
February 1996, Neurosurgery,
Takashi Watanabe, and Nobuhito Saito, and Hidetoshi Shimaguchi, and Hiroya Fujimaki, and Makoto Kamiya, and Yoichi Nakazato, and Tomio Sasaki
August 2015, Diagnostic pathology,
Copied contents to your clipboard!