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In 28 out of 40 patients with idiopathic haemochromatosis manifest diabetes mellitus could be demonstrated 19 patients required insulin. Treatment of diabetes with or without insulin was problem-free. In only two patients there was an insulin resistance which required high doses of insulin some of the time. There was a family history of diabetes in eleven patients. Minimal diabetic retinopathy in two patients was the only typical complication specific to diabetes. Severe forms of microangiopathy are seldom seen in haemochromatosis diabetes. This form of diabetes is probably mainly of genetic origin. Liver cirrhosis and fibrosis and possibly pancreatic siderosis are additional factors to be considered. A sufficiently long and intensive venesection treatment leads to clinical improvement in the diabetes in only a small fraction of the haemochromatosis patients.
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
September 1976,
Diabete & metabolisme,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
November 1978,
British medical journal,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
January 1974,
Clinical genetics,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
January 1979,
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
June 1979,
Zeitschrift fur Gastroenterologie,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
November 1978,
Klinische Padiatrie,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
February 1978,
La Nouvelle presse medicale,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
February 1982,
Horumon to rinsho. Clinical endocrinology,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
March 1979,
La Nouvelle presse medicale,
G Strohmeyer, and
H Gottesbüren, and
C Behr, and
H Sauer
July 1978,
British medical journal,
