BIOMAT Database Logo BIOMAT Database Logo

Extracardiac anomalies, aneuploidy and growth retardation in 100 consecutive fetal congenital heart defects. 1994

M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Pennsylvania Hospital, Philadelphia 19107, USA.

The importance of extracardiac anomalies in 100 consecutive fetuses with congenital heart disease was evaluated. The most common cardiac diagnoses were hypoplastic left heart syndrome in 35% and atrioventricular canal defect in 15%. Extracardiac anomalies were present in 42%, abnormal karyotype in 19% and intrauterine growth retardation in 20%. There were 45 survivors (35 required neonatal surgery, ten did not require early surgery) and 80% (36/45) of the survivors had isolated congenital heart disease. Extracardiac anomalies and abnormal karyotype were more frequently present in non-survivors (p < 0.001). Also, intrauterine growth retardation was more frequent in non-survivors (p < 0.05).

UI MeSH Term Description Entries

Related Publications

M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Congenital heart defects--chromosomal anomalies, syndromes and extracardiac malformations.
August 2007, Acta paediatrica (Oslo, Norway : 1992),
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Extracardiac anomalies and congenital heart disease.
April 1993, Seminars in perinatology,
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Congenital heart disease and extracardiac anomalies: associations and indications for fetal echocardiography.
May 1986, American journal of obstetrics and gynecology,
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Congenital heart defects and extracardiac malformations.
June 2013, Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo,
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
[Extracardiac malformations in congenital heart defects].
April 1963, Minerva cardioangiologica,
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Fetal growth retardation and structural anomalies.
December 1991, European journal of obstetrics, gynecology, and reproductive biology,
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Extracardiac birth defects in children with congenital heart defects.
May 2014, Indian pediatrics,
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Mosaic variegated aneuploidy with growth hormone deficiency and congenital heart defects.
July 2002, American journal of medical genetics,
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
High fat diet induced developmental defects in the mouse: oocyte meiotic aneuploidy and fetal growth retardation/brain defects.
January 2012, PloS one,
M L Respondek, and C N Binotto, and S Smith, and A Donnenfeld, and S R Weil, and J C Huhta
Extracardiac defects in children with congenital heart disease.
October 1979, British heart journal,
Copied contents to your clipboard!