Parathyroid scintigraphy with 99mTc-MIBI and 123I subtraction: a comparison with magnetic resonance imaging and ultrasonography. 2003

H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
Department of Radiology, Noguchi Thyroid Clinic and Hospital Foundation, Oita, Japan. hide.w@helen.ocn.ne.jp

The aim of this study was to evaluate the efficacy of 99mTc-MIBI and 123I subtraction scintigraphy for the detection of abnormal parathyroid glands to be referred for surgical treatment. Thirty-nine consecutive patients, including 35 primary and four secondary cases of hyperparathyroidism, were evaluated. 99mTc-MIBI/123I subtraction scintigraphy (MIBI/I) was performed on all patients, and the results were compared with delayed images of 99mTc-MIBI (D-MIBI), magnetic resonance imaging (MRI) and ultrasonography (US). The overall sensitivity of MIBI/I, MRI, US and D-MIBI was 55.9%, 43.4%, 50.8% and 39.0%, respectively. In cases of single-gland disease, the sensitivity of MIBI/I, MRI, US and D-MIBI was 62.1%, 48.3%, 55.2% and 44.8%, respectively. In cases of multi-gland disease, the sensitivity of MIBI/I, MRI, US and D-MIBI was 50.0%, 37.5%, 46.7% and 36.7%, respectively. In cases of parathyroid adenoma, the sensitivity of MIBI/I, MRI, US and D-MIBI was 71.4%, 50.0%, 71.4% and 50.0%, respectively. In cases of parathyroid hyperplasia, the sensitivity of MIBI/I, MRI, US and D-MIBI was 55.2%, 42.3%, 50.0% and 39.7%, respectively. It is concluded that 99mTc-MIBI/123I subtraction is more useful than the delayed imaging of 99mTc-MIBI, MRI and US.

UI MeSH Term Description Entries
D006961 Hyperparathyroidism A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.
D006962 Hyperparathyroidism, Secondary Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY. Secondary Hyperparathyroidism,Hyperparathyroidisms, Secondary,Secondary Hyperparathyroidisms
D007457 Iodine Radioisotopes Unstable isotopes of iodine that decay or disintegrate emitting radiation. I atoms with atomic weights 117-139, except I 127, are radioactive iodine isotopes. Radioisotopes, Iodine
D008279 Magnetic Resonance Imaging Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques. Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010280 Parathyroid Glands Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body. Gland, Parathyroid,Glands, Parathyroid,Parathyroid Gland
D011300 Preoperative Care Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed) Care, Preoperative,Preoperative Procedure,Preoperative Procedures,Procedure, Preoperative,Procedures, Preoperative
D011877 Radionuclide Imaging The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph. Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D005260 Female Females

Related Publications

H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
January 1987, The Japanese journal of surgery,
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
January 2014, Clinical nuclear medicine,
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
June 2016, Clinical calcium,
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
January 2017, International journal of molecular imaging,
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
July 2013, Journal of cardiac failure,
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
January 2007, Surgery today,
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
January 1999, Zentralblatt fur Chirurgie,
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
August 1995, Medizinische Klinik (Munich, Germany : 1983),
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
July 2000, Clinical nuclear medicine,
H Wakamatsu, and S Noguchi, and H Yamashita, and H Yamashita, and S Tamura, and S Jinnouchi, and S Nagamachi, and S Futami
October 2020, BMC medical imaging,
Copied contents to your clipboard!