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The minor hemoglobins AIa, AIb, and AIc were studied in mice with either genetic or chemically induced diabetes. Hemoglobin AIc was elevated approximately twofold in all the phenotypically diabetic mice studied (C57BL/KsJ-db/db, C57BL/KsJ-ob/ob, C57BL/6J-db/db, and alloxan- and streptozotocin-treated mice). Elevation of the hemoglobin AIc in C57BL/6J-db/db mice was of short duration, reflecting the transitory diabetes characteristic of these mice. The degree of increase of hemoglobin AIc levels was unrelated to severity of hyperglycemia, duration of diabetes, age of mouse, or body weight. It is not known what factor(s) dictates the steady-state concentration of hemoglobin AIc.
R J Koenig, and
D C Araujo, and
A Cerami
June 1978,
Zeitschrift fur Geburtshilfe und Perinatologie,
R J Koenig, and
D C Araujo, and
A Cerami
September 1975,
Proceedings of the National Academy of Sciences of the United States of America,
R J Koenig, and
D C Araujo, and
A Cerami
January 1980,
Acta endocrinologica. Supplementum,
R J Koenig, and
D C Araujo, and
A Cerami
December 1976,
Diabetes,
R J Koenig, and
D C Araujo, and
A Cerami
September 1978,
Ugeskrift for laeger,
R J Koenig, and
D C Araujo, and
A Cerami
April 1979,
Harefuah,
R J Koenig, and
D C Araujo, and
A Cerami
January 1982,
Osaka city medical journal,
R J Koenig, and
D C Araujo, and
A Cerami
May 1981,
The Journal of clinical endocrinology and metabolism,
R J Koenig, and
D C Araujo, and
A Cerami
December 1976,
FEBS letters,
R J Koenig, and
D C Araujo, and
A Cerami
August 1966,
Biochemistry,
