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The intraosseous ganglion is a not very well-known cystic benign bone lesion, which has to be included in the differential diagnosis of benign bone tumors. The ganglion's pathogenesis is still uncertain. Radiologically it presents all signs of a benign epiphyseal cystic tumor and can be easily differentiated from malignant changes. The characteristic X-ray signs, together with the typical location, and especially when situated in the distal medial epiphysis of the tibia, will allow a preoperative diagnosis.
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