BIOMAT Database Logo BIOMAT Database Logo

Acetophenone derivatives from Acronychia pedunculata. 2003

Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Department of Chemistry, National Cheng Kung University, Tainan, 701, Taiwan, Republic of China.

Chemical investigation on the stem and root bark of Acronychia pedunculata has resulted in the isolation of five new acetophenones, namely, acronyculatins A (1), B (2), C (3), D (4), and E (5). The structures of these metabolites were established on the basis of their 1D and 2D NMR spectroscopic and mass spectrometric data and by CD spectroscopy. The antioxidant and antityrosinase activities of these five metabolites and acrovestone (6) were evaluated. Among these compounds, 6 showed marginal antioxidant and antityrosinase activities.

UI MeSH Term Description Entries
D010946 Plants, Medicinal Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals. Herbs, Medicinal,Medicinal Herbs,Healing Plants,Medicinal Plants,Pharmaceutical Plants,Healing Plant,Herb, Medicinal,Medicinal Herb,Medicinal Plant,Pharmaceutical Plant,Plant, Healing,Plant, Medicinal,Plant, Pharmaceutical,Plants, Healing,Plants, Pharmaceutical
D002942 Circular Dichroism A change from planar to elliptic polarization when an initially plane-polarized light wave traverses an optically active medium. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Circular Dichroism, Vibrational,Dichroism, Circular,Vibrational Circular Dichroism
D004791 Enzyme Inhibitors Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. Enzyme Inhibitor,Inhibitor, Enzyme,Inhibitors, Enzyme
D000098 Acetophenones Derivatives of the simplest aromatic ketone acetophenone (of general formula C6H5C(O)CH3).
D000975 Antioxidants Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. Anti-Oxidant,Antioxidant,Antioxidant Activity,Endogenous Antioxidant,Endogenous Antioxidants,Anti-Oxidant Effect,Anti-Oxidant Effects,Anti-Oxidants,Antioxidant Effect,Antioxidant Effects,Activity, Antioxidant,Anti Oxidant,Anti Oxidant Effect,Anti Oxidant Effects,Anti Oxidants,Antioxidant, Endogenous,Antioxidants, Endogenous
D013624 Taiwan Country in eastern Asia, islands bordering the East China Sea, Philippine Sea, South China Sea, and Taiwan Strait, north of the Philippines, off the southeastern coast of China. The capital is Taipei. The alternate country name is Republic of China. Formosa,Republic of China
D014442 Monophenol Monooxygenase An enzyme of the oxidoreductase class that catalyzes the reaction between L-tyrosine, L-dopa, and oxygen to yield L-dopa, dopaquinone, and water. It is a copper protein that acts also on catechols, catalyzing some of the same reactions as CATECHOL OXIDASE. EC 1.14.18.1. Dopa Oxidase,Phenoloxidase,Tyrosinase,Cresolase,Phenol Oxidase,Phenoloxidase A,Phenoloxidase B,Monooxygenase, Monophenol,Oxidase, Dopa,Oxidase, Phenol
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D019906 Nuclear Magnetic Resonance, Biomolecular NMR spectroscopy on small- to medium-size biological macromolecules. This is often used for structural investigation of proteins and nucleic acids, and often involves more than one isotope. Biomolecular Nuclear Magnetic Resonance,Heteronuclear Nuclear Magnetic Resonance,NMR Spectroscopy, Protein,NMR, Biomolecular,NMR, Heteronuclear,NMR, Multinuclear,Nuclear Magnetic Resonance, Heteronuclear,Protein NMR Spectroscopy,Biomolecular NMR,Heteronuclear NMR,Multinuclear NMR,NMR Spectroscopies, Protein,Protein NMR Spectroscopies,Spectroscopies, Protein NMR,Spectroscopy, Protein NMR
D020128 Inhibitory Concentration 50 The concentration of a compound needed to reduce population growth of organisms, including eukaryotic cells, by 50% in vitro. Though often expressed to denote in vitro antibacterial activity, it is also used as a benchmark for cytotoxicity to eukaryotic cells in culture. IC50,Concentration 50, Inhibitory

Related Publications

Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Cytotoxic prenylated acetophenone dimers from Acronychia pedunculata.
July 2012, Journal of natural products,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Three acetophenones from Acronychia pedunculata.
April 2014, Journal of natural medicines,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
A new polyphenolic isoprenylated acetophenone dimer from the stem bark of Acronychia pedunculata (L.) Miq.
April 2023, Natural product research,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Acetophenone Monomers from Acronychia trifoliolata.
November 2016, Journal of natural products,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Isolation and identification of new prenylated acetophenone derivatives from Acronychia oligophlebia.
August 2019, Natural product research,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Six new prenylated acetophenone derivatives from the leaves of Acronychia oligophlebia.
September 2015, Fitoterapia,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Acroquinolones A and B, two polyphenolic isoprenylated acetophenone-quinolone hybrids with anti-proliferative activities from Acronychia pedunculata (L.) Miq.
June 2022, Natural product research,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
New Acetophenone Derivatives from Acronychia oligophlebia and Their Anti-inflammatory and Antioxidant Activities.
May 2018, Chemistry & biodiversity,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Acetophenones from Acronychia pedunculata and their Cancer Chemopreventive Activity.
September 2016, Natural product communications,
Chung-Ren Su, and Ping-Chung Kuo, and Meei-Ling Wang, and Meei-Jen Liou, and Amooru G Damu, and Tian-Shung Wu
Acronyrones A-C, unusual prenylated acetophenones from Acronychia pedunculata.
November 2022, Fitoterapia,
Copied contents to your clipboard!