Thirty-five cases of deep second burn of the hand (40 hands) were treated with autodermabrader to remove necrotic tissue. In comparison with 30 cases treated with tangential excision, bleeding was less and operation time was decreased markedly (P < 0.01) in the autodermabrader group. Histopathological study of the dermabrased wound was made to evaluate the mechanism of decreased bleeding. We consider that the new operative modality with autodermabader could be used in the treatment of deep II degree burn in exposed areas.