-transparent.png){kind=logo}
A 70-year-old woman was hospitalized for status asthmaticus. The level of CRP was high and chest roentgenogram showed infiltrative shadows in the left middle lung field. Artificial respiration and continuous infusion of methylprednisolone and aminophylline 750 mg/24 hr were performed. Eight hours after admission, seizures suddenly occurred. At this time, brain CT showed no abnormal findings. The seizures were thought to be induced by theophylline toxicity, since serum theophylline concentration was high at 69.9 micrograms/ml. Because theophylline clearance of the patient in a clinically stable condition was normal, it was speculated that theophylline clearance was reduced during status asthmaticus. It is thought that this rare case of theophylline toxicity occurred due to reduction of theophylline clearance during status asthmaticus associated with pneumonia.
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
May 2001,
Chest,
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
December 1989,
DICP : the annals of pharmacotherapy,
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
November 1988,
Arerugi = [Allergy],
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
January 1985,
Annals of allergy,
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
February 1991,
Anaesthesia and intensive care,
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
June 2012,
The Korean journal of thoracic and cardiovascular surgery,
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
September 2016,
The Journal of asthma : official journal of the Association for the Care of Asthma,
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
January 2008,
Journal of intensive care medicine,
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
January 1999,
Journal of toxicology. Clinical toxicology,
Y Saitoh, and
T Bando, and
K Kanamori, and
J Mifune, and
F Sasaki, and
T Ishizaki, and
S Miyabo
March 1987,
American journal of diseases of children (1960),
