Stereoselective synthesis of 4'-carbon-substituted 2',3'-didehydro-2',3'-dideoxynucleosides.
1992
K Haraguchi, and
H Tanaka, and
Y Itoh, and
T Miyasaka
School of Pharmaceutical Sciences, Showa University, Tokyo, Japan.
UI
MeSH Term
Description
Entries
D012825
Silicon
A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].
Silicon-28,Silicon 28
D013237
Stereoisomerism
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
A trace element that is required in bone formation. It has the atomic symbol Sn, atomic number 50, and atomic weight 118.71.
Stannum
D015224
Dideoxynucleosides
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.