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Flavonoids and isoflavonoids with antiplasmodial activities from the root bark of Erythrina abyssinica. 2003
Abiy Yenesew, and
Solomon Derese, and
Beatrice Irungu, and
Jacob O Midiwo, and
Norman C Waters, and
Pamela Liyala, and
Hoseah Akala, and
Matthias Heydenreich, and
Martin G Peter
Department of Chemistry, University of Nairobi, Nairobi, Kenya. ayenesew@uonbi.ac.ke
From the root bark of Erythrina abyssinica a new pterocarpene [3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene] and a new isoflav-3-ene [7,4'-dihydroxy-2',5'-dimethoxyisoflav-3-ene] were isolated. In addition, the known compounds erycristagallin, licoagrochalcone A, octacosyl ferulate and triacontyl 4-hydroxycinnamate were identified. The structures were determined on the basis of spectroscopic evidence. The crude extract and the flavonoids and isoflavonoids obtained from the roots of this plant showed antiplasmodial activities.
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