Emerging issues in vaccine economics: perspectives from the USA. 2002

Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA 02215, USA. tracy_lieu@harvardpilgrim.org

Economic studies of vaccines, including vaccine development and delivery issues, are increasingly needed to inform policy recommendations and programmatic decisions in the USA. This need arises from the increasing costs of vaccines, the complexity of the US healthcare system and the limited number of vaccine manufacturers in the market. We have developed a national research agenda in domestic and global vaccine economics by conducting key informant interviews with 42 experts and inviting ideas from an additional 128 experts. To assess priorities among the 129 ideas that were generated, we asked 15 experts representing a broad range of perspectives to rank the ideas and we analyzed their votes. The highest-ranking domestic research ideas included evaluating: the costs of vaccine shortages, the cost-effectiveness of potential human papillomavirus vaccination and adult and adolescent pertussis vaccination programs and the cost-effectiveness of universal vaccine purchase programs for adults as well as children. The highest-ranking globally-oriented ideas included developing a resource allocation model to support the best vaccination program decisions with limited funds and assessing the cost-effectiveness of HIV, rotavirus, meningococcal and malaria vaccines in developing countries. To optimize the usefulness of vaccine economics research, conceptual issues, such as how to set values for the prevention of illness and how to maximize social equity through investments in vaccines, must be addressed.

UI MeSH Term Description Entries
D010567 Pertussis Vaccine A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed) Vaccine, Pertussis
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D003362 Cost-Benefit Analysis A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. In contrast a cost effectiveness in general compares cost with qualitative outcomes. Cost and Benefit,Cost-Benefit Data,Benefits and Costs,Cost Benefit,Cost Benefit Analysis,Cost-Utility Analysis,Costs and Benefits,Economic Evaluation,Marginal Analysis,Analyses, Cost Benefit,Analysis, Cost Benefit,Analysis, Cost-Benefit,Analysis, Cost-Utility,Analysis, Marginal,Benefit and Cost,Cost Benefit Analyses,Cost Benefit Data,Cost Utility Analysis,Cost-Benefit Analyses,Cost-Utility Analyses,Data, Cost-Benefit,Economic Evaluations,Evaluation, Economic,Marginal Analyses
D003625 Data Collection Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data. Data Collection Methods,Dual Data Collection,Collection Method, Data,Collection Methods, Data,Collection, Data,Collection, Dual Data,Data Collection Method,Method, Data Collection,Methods, Data Collection
D003906 Developing Countries Countries in the process of change with economic growth, that is, an increase in production, per capita consumption, and income. The process of economic growth involves better utilization of natural and human resources, which results in a change in the social, political, and economic structures. LMICs,Less-Developed Countries,Low Income Countries,Low and Middle Income Countries,Lower-Middle-Income Country,Middle Income Countries,Third-World Countries,Under-Developed Countries,Developing Nations,Least Developed Countries,Less-Developed Nations,Third-World Nations,Under-Developed Nations,Countries, Middle Income,Countries, Third-World,Country, Least Developed,Country, Less-Developed,Country, Low Income,Country, Lower-Middle-Income,Country, Middle Income,Country, Third-World,Country, Under-Developed,Developed Country, Least,Developing Country,Developing Nation,Least Developed Country,Less Developed Countries,Less Developed Nations,Less-Developed Country,Less-Developed Nation,Low Income Country,Lower Middle Income Country,Lower-Middle-Income Countries,Middle Income Country,Nation, Less-Developed,Nation, Third-World,Nation, Under-Developed,Third World Countries,Third World Nations,Third-World Country,Third-World Nation,Under Developed Countries,Under Developed Nations,Under-Developed Country,Under-Developed Nation
D005104 Expert Testimony Presentation of pertinent data by one with special skill or knowledge representing mastery of a particular subject. Expert Opinion,Expert Witness,Expert Opinions,Expert Testimonies,Expert Witnesses,Opinion, Expert,Testimony, Expert,Witness, Expert,Witnesses, Expert
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D014481 United States A country in NORTH AMERICA between CANADA and MEXICO.
D014611 Vaccination Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis. Immunization, Active,Active Immunization,Active Immunizations,Immunizations, Active,Vaccinations

Related Publications

Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
January 2023, Gut microbes,
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
December 2007, Expert review of vaccines,
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
January 1995, Nursing economic$,
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
January 1994, Illinois dental journal,
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
June 2013, Cancer,
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
December 2011, Medical care,
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
November 2010, Expert review of vaccines,
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
February 1993, Journal de radiologie,
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
January 2019, International review of psychiatry (Abingdon, England),
Tracy A Lieu, and Kimberly M Thompson, and Lisa A Prosser, and Megan A O'Brien, and Hussain R Yusuf, and Abigail M Shefer, and Milton C Weinstein, and Donna L Rickert
January 2010, Cancer treatment and research,
Copied contents to your clipboard!