Biomaterial Database

Aorta wall quantitative alterations due to different long-term high-fat diet in rats. 2003

Marcia Barbosa Aguila, and Carlos Alberto Mandarim-de-Lacerda

Biomedical Center, Institute of Biology, State University of Rio de Janeiro, 20551-030 Rio de Janeiro, Brazil. mandarim@uerj.br

Twenty Wistar male rats, with ages varying from 21 days to 12 months, were fed with diets supplemented by soybean oil (S group), canola oil (CA group), lard and egg yolk (LE group), and canola plus lard and egg yolk (CA+LE group). The LE group presented the highest heart mass/body mass ratio and the highest blood pressure as well. The aortic structure suffered a number of alterations, from CA rats group (minor alterations) to LE and CA+LE rats group (major alterations). The CA group showed the smallest aorta thickness. No significant differences among groups were found concerning the number of aortic lamellae and the density of tunica media smooth muscle nuclei. Surface density of the aortic lamellae was greater in the CA group and smaller in the LE group. These results suggest that the dietary intake of canola oil could attenuate the aorta structure aging process with a favorable BP maintenance.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D001794	Blood Pressure	PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.	Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D004032	Diet	Regular course of eating and drinking adopted by a person or animal.	Diets
D004041	Dietary Fats	Fats present in food, especially in animal products such as meat, meat products, butter, ghee. They are present in lower amounts in nuts, seeds, and avocados.	Fats, Dietary,Dietary Fat,Fat, Dietary
D004530	Egg Yolk	Cytoplasm stored in an egg that contains nutritional reserves for the developing embryo. It is rich in polysaccharides, lipids, and proteins.	Egg Yolks,Yolk, Egg,Yolks, Egg
D005229	Fatty Acids, Monounsaturated	Fatty acids which are unsaturated in only one position.	Monounsaturated Fatty Acid,Acid, Monounsaturated Fatty,Acids, Monounsaturated Fatty,Fatty Acid, Monounsaturated,Monounsaturated Fatty Acids
D000074262	Rapeseed Oil	PLANT OILS derived from RAPESEED species known as BRASSICA NAPUS.	Canadian Oil,Canola Oil,LEAR Oil,Low Erucic Acid Rapeseed Oil,Oil, Canadian,Oil, Canola,Oil, LEAR,Oil, Rapeseed
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001013	Aorta, Thoracic	The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.	Aorta, Ascending,Aorta, Descending,Aortic Arch,Aortic Root,Arch of the Aorta,Descending Aorta,Sinotubular Junction,Ascending Aorta,Thoracic Aorta,Aortic Roots,Arch, Aortic,Ascending Aortas,Junction, Sinotubular,Root, Aortic,Sinotubular Junctions
D017208	Rats, Wistar	A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.	Wistar Rat,Rat, Wistar,Wistar Rats