BIOMAT Database Logo BIOMAT Database Logo

[Influence of autonomic nervous system on electrolyte abnormalities in children with mitral valve prolapse]. 2003

Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
Klinika Kardiologii i Nefrologii Dzieciecej Akademii Medycznej w Poznaniu. wbobk@mp.pl

Measurement of the heart rate variability enables to assess the activity of the autonomous nervous system. The aim of the study was to evaluate the possible relationship between clinical status, serum sodium (Na), potassium (K), calcium (Ca), magnesium concentrations and HRV in children with mitral valve prolapse. The study group consisted of 151 children with MVP (age +/- SD: 12.2 +/- 3.1 years). Thirty patients out of the MVP group were symptomatic and 121 were asymptomatic. The total number of 165 healthy children (age +/- SD: 12.3 +/- 3.7 years) were included into the control group. We assessed power spectrum of HRV (low frequency component--LF, high frequency component--HF, and LF/HF ratio) from 5-minute recording during daytime and night. Serum Mg (p < 0.00001) and K (p < 0.03) concentrations were significantly lower in MVP group as compared to healthy children. A marked decrease in Mg concentration was observed in symptomatic children with MVP as compared to asymptomatic patients (p < 0.0001). A significant positive correlation was found between Mg concentration and HF and HF n.u. components (daytime and night) and significant negative correlation was observed between Mg concentration and LF and LF n.u. (daytime and night) parameters and LF/HF ratio (daytime and night). Symptomatic children with MVP had significantly higher LF n.u. and LF/HF ratio and a lower HF n.u. as compared to asymptomatic patients. The autonomic changes in MVP children (reduction in parasympathetic tone with sympathetic predominance) were associated with decreased serum Mg concentration and higher prevalence of clinical symptoms. Mg supplementation seems to be a prudent approach in symptomatic children with MVP.

UI MeSH Term Description Entries
D008945 Mitral Valve Prolapse Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA. Floppy Mitral Valve,Mitral Click-Murmur Syndrome,Systolic Click-Murmur Syndrome,Click-Murmur Syndrome,Mitral Valve Prolapse Syndrome,Prolapsed Mitral Valve,Click Murmur Syndrome,Click-Murmur Syndrome, Mitral,Click-Murmur Syndrome, Systolic,Click-Murmur Syndromes,Floppy Mitral Valves,Mitral Click Murmur Syndrome,Mitral Valve Prolapses,Mitral Valve, Floppy,Mitral Valve, Prolapsed,Mitral Valves, Floppy,Mitral Valves, Prolapsed,Prolapse, Mitral Valve,Prolapsed Mitral Valves,Prolapses, Mitral Valve,Syndrome, Click-Murmur,Syndrome, Mitral Click-Murmur,Syndrome, Systolic Click-Murmur,Syndromes, Click-Murmur,Systolic Click Murmur Syndrome,Valve Prolapse, Mitral,Valve Prolapses, Mitral,Valve, Prolapsed Mitral,Valves, Prolapsed Mitral
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D004573 Electrolytes Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed) Electrolyte
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D001342 Autonomic Nervous System Diseases Diseases of the AUTONOMIC NERVOUS SYSTEM, including sympathetic, parasympathetic, and enteric nervous systems. Autonomic Disorders,Central Autonomic Nervous System Diseases,Disorders of the Autonomic Nervous System,Dysautonomia,Nervous System Diseases, Autonomic,Nervous System Diseases, Parasympathetic,Nervous System Diseases, Sympathetic,Non-Familial Dysautonomia,Parasympathetic Nervous System Diseases,Peripheral Autonomic Nervous System Diseases,Sympathetic Nervous System Diseases,ANS (Autonomic Nervous System) Diseases,ANS Diseases,Autonomic Central Nervous System Diseases,Autonomic Diseases,Autonomic Nervous System Disorders,Autonomic Peripheral Nervous System Diseases,Segmental Autonomic Dysfunction,ANS Disease,Autonomic Disease,Autonomic Disorder,Autonomic Dysfunction, Segmental,Autonomic Dysfunctions, Segmental,Disorder, Autonomic,Dysautonomia, Non-Familial,Dysautonomias,Non Familial Dysautonomia,Non-Familial Dysautonomias,Segmental Autonomic Dysfunctions

Related Publications

Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
[Autonomic nervous system function in mitral valve prolapse].
January 1980, Kardiologia polska,
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
[Relationship between mitral valve prolapse and autonomic nervous system dysfunction].
February 1990, Harefuah,
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
Effects of Mitral Valve Prolapse on Heart Rate Variability and the Autonomic Nervous System in Children.
July 2022, The journal of Tehran Heart Center,
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
[Mitral valve prolapse syndrome. Arrhythmia, abnormalities of the ventricular contraction and dysfunction of the autonomic nervous system].
January 1980, Revista espanola de cardiologia,
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
[Changes of the nervous system in mitral valve prolapse].
January 1989, Sovetskaia meditsina,
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
Autonomic function in mitral valve prolapse.
October 1987, Lancet (London, England),
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
Autonomic function in mitral valve prolapse.
November 1979, Circulation,
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
Autonomic dysfunction in women with mitral valve prolapse.
October 1979, Circulation,
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
[Mitral valve prolapse. Association with skeletal abnormalities].
February 1984, Presse medicale (Paris, France : 1983),
Waldemar Bobkowski, and Jacek Zachwieja, and Aldona Siwińska, and Bartłomiej Mroziński, and Alina Rzeźnik-Bieniaszewska, and Janusz Maciejewski
Electrocardiographic abnormalities in mitral valve prolapse.
July 1992, The American journal of cardiology,
Copied contents to your clipboard!