BIOMAT Database Logo BIOMAT Database Logo

Fibrillary glomerulonephritis with hypocomplementemia. 2003

Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
First Department of Internal Medicine, Yamagata University School of Medicine, Yamagata.

A 59-year-old man was referred for evaluation of nephrotic syndrome. The patient was diagnosed to have rheumatoid arthritis and had been treated for 10 years. Renal biopsy showed mesangial proliferation with small nodular formations, which were determined as fibrillary deposits (average diameter: 20 nm) by electromicroscopy. Congo-red stain was negative. The laboratory findings revealed hypocomplementemia and lambda type of Bence-Jones protein in urine without other systemic diseases including multiple myeloma. Immunosuppressive therapy did not attenuate the nephrotic-range proteinuria. Such a case of fibrillary glomerulonephritis with hypocomplementemia is rare.

UI MeSH Term Description Entries
D007166 Immunosuppressive Agents Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. Immunosuppressant,Immunosuppressive Agent,Immunosuppressants,Agent, Immunosuppressive,Agents, Immunosuppressive
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009404 Nephrotic Syndrome A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction. Childhood Idiopathic Nephrotic Syndrome,Frequently Relapsing Nephrotic Syndrome,Multi-Drug Resistant Nephrotic Syndrome,Pediatric Idiopathic Nephrotic Syndrome,Steroid-Dependent Nephrotic Syndrome,Steroid-Resistant Nephrotic Syndrome,Steroid-Sensitive Nephrotic Syndrome,Multi Drug Resistant Nephrotic Syndrome,Nephrotic Syndrome, Steroid-Dependent,Nephrotic Syndrome, Steroid-Resistant,Nephrotic Syndrome, Steroid-Sensitive,Nephrotic Syndromes,Steroid Dependent Nephrotic Syndrome,Steroid Resistant Nephrotic Syndrome,Steroid Sensitive Nephrotic Syndrome,Steroid-Dependent Nephrotic Syndromes,Steroid-Resistant Nephrotic Syndromes,Steroid-Sensitive Nephrotic Syndromes,Syndrome, Nephrotic,Syndrome, Steroid-Sensitive Nephrotic
D003165 Complement System Proteins Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY). Complement Proteins,Complement,Complement Protein,Hemolytic Complement,Complement, Hemolytic,Protein, Complement,Proteins, Complement,Proteins, Complement System
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000893 Anti-Inflammatory Agents Substances that reduce or suppress INFLAMMATION. Anti-Inflammatory Agent,Antiinflammatory Agent,Agents, Anti-Inflammatory,Agents, Antiinflammatory,Anti-Inflammatories,Antiinflammatories,Antiinflammatory Agents,Agent, Anti-Inflammatory,Agent, Antiinflammatory,Agents, Anti Inflammatory,Anti Inflammatories,Anti Inflammatory Agent,Anti Inflammatory Agents
D001172 Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. Rheumatoid Arthritis
D001536 Bence Jones Protein An abnormal protein with unusual thermosolubility characteristics that is found in the urine of patients with MULTIPLE MYELOMA. Bence Jones Protein Den,Bence Jones Protein SUT,Jones Protein, Bence,Protein, Bence Jones
D015432 Glomerulonephritis, Membranoproliferative Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN. C3G Complement 3 Glomerulopathy,Complement 3 Glomerulopathies,Complement 3 Glomerulopathy,Glomerulonephritis, Mesangiocapillary,MPGN Membranoproliferative Glomerulonephritis,Membranoproliferative Glomerulonephritis,Mesangiocapillary Glomerulonephritis,DDD MPGNII,Dense Deposit Disease,Glomerulonephritis, Hypocomplementemic,MPGNII,Membranoproliferative Glomerulonephritis Type II,Membranoproliferative Glomerulonephritis, Type I,Membranoproliferative Glomerulonephritis, Type II,Membranoproliferative Glomerulonephritis, Type III,Mesangiocapillary Glomerulonephritis, Type I,Mesangiocapillary Glomerulonephritis, Type II,Subendothelial Membranoproliferative Glomerulonephritis,Type II MPGN,DDD MPGNIIs,Glomerulonephritides, MPGN Membranoproliferative,Glomerulonephritides, Membranoproliferative,Glomerulonephritis, MPGN Membranoproliferative,Glomerulopathies, Complement 3,Glomerulopathy, Complement 3,Hypocomplementemic Glomerulonephritides,Hypocomplementemic Glomerulonephritis,MPGN Membranoproliferative Glomerulonephritides,MPGN, Type II,MPGNII, DDD,MPGNIIs,Membranoproliferative Glomerulonephritides,Membranoproliferative Glomerulonephritides, MPGN,Membranoproliferative Glomerulonephritis, MPGN,Membranoproliferative Glomerulonephritis, Subendothelial,Mesangiocapillary Glomerulonephritides,Type II MPGNs

Related Publications

Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
Fibrillary glomerulonephritis with hepatitis C viral infection and hypocomplementemia.
January 2008, Renal failure,
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
Glomerulonephritis with associated hypocomplementemia and crescents: an unusual case of fibrillary glomerulonephritis.
August 1995, Journal of the American Society of Nephrology : JASN,
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
A case of fibrillary glomerulonephritis with unusual IgM deposits and hypocomplementemia.
July 2008, Pediatric nephrology (Berlin, Germany),
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
Fibrillary Glomerulonephritis with Atypical Immunoglobulin M Deposits and Hypocomplementemia Revealed Human Immunodeficiency Virus Infection.
January 2021, Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia,
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
Chronic membranoproliferative glomerulonephritis with hypocomplementemia.
December 1969, Transplantation proceedings,
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
[Chronic proliferative-membranaceous glomerulonephritis with hypocomplementemia].
April 1975, Polski tygodnik lekarski (Warsaw, Poland : 1960),
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
Editorial: Hypocomplementemia in glomerulonephritis.
October 1975, Southern medical journal,
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
Studies on chronic membranoproliferative glomerulonephritis with hypocomplementemia.
September 1971, The Journal of experimental medicine,
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
Studies on chronic membranoproliferative glomerulonephritis with hypocomplementemia.
September 1971, The Journal of experimental medicine,
Satoshi Suzuki, and Tsuneo Konta, and Ryo Koizumi, and Wakako Nishida, and Hiroshi Abiko, and Isao Kubota
[Fibrillary glomerulonephritis].
January 2003, Sbornik lekarsky,
Copied contents to your clipboard!