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A reactive ability of immunocompetent cells was assessed by the level of cytokines TNF alpha and IL-8 estimated by enzyme immunoassay ("Genzyme diagnostics" kit) in 18 patients with chronic obstructive bronchitis (mean age 58 +/- 4.2 years, mean duration of the disease 11.2 +/- 5.2 years) and 15 control patients matched for age, with normal external respiration function, free of chronic bronchopulmonary pathology and allergic diseases. The greatest differences in cytokine levels were registered between the control group and patients with moderate generalized irreversible obstruction. These patients had similar basal and E. coli LPS induced synthesis of the above cytokines showing the lack of cell reserves, adequate immune response to exogenic antigen.
E P Kalinina, and
E V Isachenko, and
G I Tsyvkina
January 1995,
Problemy tuberkuleza,
E P Kalinina, and
E V Isachenko, and
G I Tsyvkina
January 1988,
Terapevticheskii arkhiv,
E P Kalinina, and
E V Isachenko, and
G I Tsyvkina
January 2004,
Problemy tuberkuleza i boleznei legkikh,
E P Kalinina, and
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G I Tsyvkina
January 2001,
Klinicheskaia meditsina,
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January 2005,
Problemy tuberkuleza i boleznei legkikh,
E P Kalinina, and
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G I Tsyvkina
April 1992,
Likars'ka sprava,
E P Kalinina, and
E V Isachenko, and
G I Tsyvkina
January 2002,
Terapevticheskii arkhiv,
E P Kalinina, and
E V Isachenko, and
G I Tsyvkina
December 1983,
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E P Kalinina, and
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G I Tsyvkina
January 1987,
Problemy tuberkuleza,
E P Kalinina, and
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G I Tsyvkina
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Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury,
