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Ultrastructure of the pineal gland after gamma-irradiation under conditions of inhibition of adrenocortical function. 2003
Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk. popoutch@mrrc.obninsk.ru
Electron microscopy showed that whole-body gamma-irradiation in sublethal doses led to the appearance of injuries in pinealocytes, glial cells, and vessels of the pineal gland in rats. Limitation of the nonspecific effect of gamma-irradiation via inhibition of adrenocortical function with metopirone in physiological doses reduced the radiation-induced ultrastructural damage to the pineal gland.
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