BIOMAT Database Logo BIOMAT Database Logo

1-(4-methylamino-1,2,5-thiadiazole-3-carbonyl)thiosemicarbazide. 2003

Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Institute of Applied Physics, Academy of Sciences of Moldova, Academy str. 5, MD2028 Chisinau, Moldova. fonari.xray@phys.asm.md

In the title compound, C(5)H(8)N(6)OS(2), the supramolecular architecture is sustained by two N--H...O and three N--H...S hydrogen bonds, and by N.S electrostatic interactions. The hydrogen-bond network generates a sheet structure, which extends in the a and b directions and is one c-cell dimension thick. These extended sheets are then linked across inversion centres in the c direction by N...S electrostatic interactions, thus forming a three-dimensional network. The principal intermolecular dimensions include N(H)...O distances of 2.8393 (17) and 3.0268 (16) A, N(H)...S distances in the range 3.2896 (14)-3.5924 (16) A and N...S distances of 3.0822 (16) A.

UI MeSH Term Description Entries

Related Publications

Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
4-[4-(4-Amino-1,2,5-oxadiazol-3-yl)-1,2,5-oxadiazol-3-yl]-1,2,5-oxadiazol-3-amine.
May 2012, Acta crystallographica. Section E, Structure reports online,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
In vitro cytogenetic activity of 3-amino-4-[4-(dimethylamino)phenyl]-4,5-dihydro-1,2,5-thiadiazole 1,1-dioxide.
November 2021, Drug and chemical toxicology,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Immunoregulatory effects of 4-(4-chlorophenyl)-1-(5-amino-3-methylisoxazole-4-carbonyl)-thiosemicarbazide (06K) in non-immunized and SRBC-immunized mice.
December 2016, The Journal of pharmacy and pharmacology,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Synthesis of related compounds of thiosemicarbazide. IV. 1-(1, 3, 4-Thiadiazol-2-yl)-2-pyrazolin-5-one and tetrazolo(4, 5-a)-1,3, 4-thiadiazole derivatives.
August 1958, Chemical & pharmaceutical bulletin,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Pharmacological activity of 5-phenyl-1:3:4-thiadiazole (L 1538), 2-amino-5-phenyl-1:3:4-thiadiazole (L 1460) and 2-amino-5-(2'-thienyl)-1:3:4-thiadiazole (L 1458).
December 1958, British journal of pharmacology and chemotherapy,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Synthesis and antifungal activities of alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamates and S-alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamothioates.
May 2005, Journal of agricultural and food chemistry,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Apparent irreversible H2-receptor blocking and prolonged gastric antisecretory activities of 3-N-(3-[3-(1-piperidinomethyl)phenoxy]propyl) amino-4-amino-1,2,5-thiadiazole-1-oxide (L-643, 441).
March 1983, The Journal of pharmacology and experimental therapeutics,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Structure of 4-(3-chlorophenyl)thiosemicarbazide.
January 1991, Acta crystallographica. Section C, Crystal structure communications,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Vibrational and quantum chemical investigation of cyclization of thiosemicarbazide group in 1-benzoyl-4-phenyl-3-thiosemicarbazide.
November 2014, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,
Marina S Fonari, and Yurii A Simonov, and Janusz Lipkowski, and Arkadii A Yavolovskii
Synthesis and H2-antagonist properties of some 1,2,5-thiadiazole-1-oxide derivatives.
December 1992, Farmaco (Societa chimica italiana : 1989),
Copied contents to your clipboard!