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We studied the efficiency and safety of a new homeopathic preparation Artrofoon containing affinely purified antibodies to tumor necrosis factor-alpha in the therapy of patients with rheumatoid arthritis. Artrofoon produced a positive antiinflammatory effect on the course of rheumatoid arthritis. This preparation reduced the severity of arthralgia (indexes of Li and Ritchie) and morning stiffness and decreased the erythrocyte sedimentation rate and contents of rheumatoid factor and C-reactive protein. One-month therapy improved the state of patients. Artrofoon was well tolerable. The preparation did not cause the ulcerogenic and nephrotoxic effects. Artrofoon holds much promise for combination therapy of patients with rheumatoid arthritis (including severe articular-and-visceral forms) and complications after treatment with nonsteroid antiinflammatory preparations.
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
January 2003,
Bulletin of experimental biology and medicine,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
October 1998,
Zeitschrift fur Rheumatologie,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
February 2008,
Arthritis and rheumatism,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
December 1993,
Arthritis and rheumatism,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
January 1997,
Advances in immunology,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
September 2009,
Journal of periodontology,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
January 2001,
Autoimmunity,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
November 2000,
Arthritis and rheumatism,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
January 2010,
Clinical and experimental rheumatology,
L V Kozlovskaya, and
N A Mukhin, and
V V Rameev, and
I A Sarkisova, and
O I Epstein
January 1993,
Bollettino della Societa italiana di biologia sperimentale,
