Biomaterial Database

[Lethal aspergillosis of the paranasal sinuses (author's transl)]. 1975

M Weidenbecher, and G Brandt

A 73-year-old farmer developed both blindness of his left eye and a 20 kg loss of weight within 3 months. A protrusion of his left eyebulb was observed, which suggested the retrobulbar growth of a tumor. Histologic examinations of several biopsies from the paranasal sinuses evidenced polypoid tissue with signs of chronic inflammation, ulceration, and fungus infection. The patient died in cerebral coma. The autopsy revealed a destruction of the cranial base by a chronic mycocenic osteomyelitis, a frontal lobe abscess, and a fungus invasion of the internal carotid artery with circumscribed thrombosis of this vessel and adjacent encephalomalazie. The fungus was identified morphologically as aspergillus, a rare differential diagnosis to paranasal malignancies.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D010019	Osteomyelitis	INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.	Osteomyelitides
D010255	Paranasal Sinus Neoplasms	Tumors or cancer of the PARANASAL SINUSES.	Cancer of Paranasal Sinus,Neoplasms, Paranasal Sinus,Paranasal Sinus Cancer,Cancer, Paranasal Sinus,Cancers, Paranasal Sinus,Neoplasm, Paranasal Sinus,Paranasal Sinus Cancers,Paranasal Sinus Neoplasm
D010256	Paranasal Sinuses	Air-filled spaces located within the bones around the NASAL CAVITY. They are extensions of the nasal cavity and lined by the ciliated NASAL MUCOSA. Each sinus is named for the cranial bone in which it is located, such as the ETHMOID SINUS; the FRONTAL SINUS; the MAXILLARY SINUS; and the SPHENOID SINUS.	Nasal Sinuses,Osteomeatal Complex,Ostiomeatal Complex,Ostiomeatal Unit,Sinonasal Tract,Supraorbital Ethmoid Cell,Cell, Supraorbital Ethmoid,Complex, Osteomeatal,Ethmoid Cell, Supraorbital,Osteomeatal Complices,Ostiomeatal Complices,Ostiomeatal Units,Sinonasal Tracts,Sinuses, Nasal,Supraorbital Ethmoid Cells,Tract, Sinonasal
D012141	Respiratory Tract Infections	Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.	Respiratory System Infections,Upper Respiratory Tract Infection,Upper Respiratory Tract Infections,Infections, Respiratory,Infections, Respiratory Tract,Infections, Upper Respiratory,Infections, Upper Respiratory Tract,Respiratory Infections,Upper Respiratory Infections,Infection, Respiratory System,Infection, Respiratory Tract,Respiratory Infection, Upper,Respiratory System Infection,Respiratory Tract Infection
D001922	Brain Abscess	A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)	Brain Abscess, Child,Brain Abscess, Multiple,Brain Abscess, Pyogenic,Brain Abscess, Sterile,Cerebral Abscess,Abscess, Brain,Abscess, Cerebral,Abscess, Child Brain,Abscess, Multiple Brain,Abscess, Pyogenic Brain,Abscesses, Cerebral,Abscesses, Multiple Brain,Brain Abscesses,Brain Abscesses, Multiple,Brain Abscesses, Pyogenic,Brain Abscesses, Sterile,Cerebral Abscesses,Child Brain Abscess,Multiple Brain Abscess,Multiple Brain Abscesses,Pyogenic Brain Abscess,Pyogenic Brain Abscesses,Sterile Brain Abscess,Sterile Brain Abscesses
D002341	Carotid Artery Thrombosis	Blood clot formation in any part of the CAROTID ARTERIES. This may produce CAROTID STENOSIS or occlusion of the vessel, leading to TRANSIENT ISCHEMIC ATTACK; CEREBRAL INFARCTION; or AMAUROSIS FUGAX.	Thrombosis, Carotid Artery,Carotid Thrombosis,Common Carotid Artery Thrombosis,External Carotid Artery Thrombosis,Internal Carotid Artery Thrombosis,Thrombosis, Carotid,Thrombosis, Common Carotid Artery,Thrombosis, External Carotid Artery,Thrombosis, Internal Carotid Artery,Carotid Artery Thromboses
D002343	Carotid Artery, Internal	Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.	Arteries, Internal Carotid,Artery, Internal Carotid,Carotid Arteries, Internal,Internal Carotid Arteries,Internal Carotid Artery
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005625	Frontal Lobe	The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.	Brodmann Area 8,Brodmann's Area 8,Frontal Cortex,Frontal Eye Fields,Lobus Frontalis,Supplementary Eye Field,Area 8, Brodmann,Area 8, Brodmann's,Brodmanns Area 8,Cortex, Frontal,Eye Field, Frontal,Eye Field, Supplementary,Eye Fields, Frontal,Frontal Cortices,Frontal Eye Field,Frontal Lobes,Lobe, Frontal,Supplementary Eye Fields