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Synthesis of heterocyclic and carbocyclic fluoro-olefins by ring-closing metathesis. 2003

Sofia S Salim, and Richard K Bellingham, and Vachiraporn Satcharoen, and Richard C D Brown
Department of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.

[reaction: see text] Ring-closing metathesis (RCM) of vinyl fluoride-containing dienes in the presence of ruthenium alkylidene carbene complex 11 proceeded efficiently to give six- and seven-membered cyclic vinyl fluorides. The RCM reaction was used to prepare amine- and sulfamide-linked cyclo-olefins, as well as carbocyclic systems, from a simple commercial fluoro-olefin.

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