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The method of serial dilutions on the Hottinger agar was applied to comparative assay of antibiotic sensitivity in 50 strains of the plague microbe isolated abroad and in 5 strains isolated in the plague focus in the Central Caucasus. The antibiotics used in the assay were the following: streptomycin, gentamicin, doxycycline, monomycin, kanamycin, tetracycline, erythromycin, ristomycin, lincomycin and polymyxin M. Irrespective of the origin, all the isolates were resistant to erythromycin, lincomycin and polymyxin M. The levels of the sensitivity to the other antibiotics were different. The data serve as a ground for the statement that there is no tendency to development of antibiotic resistance in the plague microbe in patients treated with high doses of the antibiotics and mainly streptomycin. Along with streptomycin, such antibiotics as gentamicin, tetracycline, doxycycline and kanamycin are useful in the therapy of plague and require further investigation.
G N Galenko, and
A K Akiev, and
V E Tarasova
May 1981,
Antibiotiki,
G N Galenko, and
A K Akiev, and
V E Tarasova
August 1973,
Antibiotiki,
G N Galenko, and
A K Akiev, and
V E Tarasova
March 1976,
Voenno-meditsinskii zhurnal,
G N Galenko, and
A K Akiev, and
V E Tarasova
January 1967,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
G N Galenko, and
A K Akiev, and
V E Tarasova
March 1977,
Antibiotiki,
G N Galenko, and
A K Akiev, and
V E Tarasova
July 1977,
Antibiotiki,
G N Galenko, and
A K Akiev, and
V E Tarasova
September 1962,
Die Medizinische Welt,
G N Galenko, and
A K Akiev, and
V E Tarasova
December 1979,
Genetika,
G N Galenko, and
A K Akiev, and
V E Tarasova
January 1973,
Voprosy meditsinskoi khimii,
G N Galenko, and
A K Akiev, and
V E Tarasova
January 1966,
Medycyna doswiadczalna i mikrobiologia,
