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To evaluate the effectiveness of administration of oral cisapride in patients with gastro-esophageal reflux, we studied 25 children, aged 1 month-7 years (mean 16.2 months) affected with GER. At the time of diagnosis and 8 weeks after treatment, patients were clinically evaluated and underwent a 24-hour continuous esophageal pH-monitoring. After treatment a complete regression of symptoms was observed in 20/25 patients. Moreover we recorded a significant reduction in the percentage of reflux time (p < 0.0001) and in the Jolley score (p < 0.0001), a very accurate scoring system to evaluate the pH-metric tracing, after treatment. It is concluded that cisapride is a useful agent both for the relief of symptoms and for the improvement of pH-metric parameters in children with GER disease.
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
November 1997,
Journal of pediatric gastroenterology and nutrition,
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
July 1999,
Journal of pediatric gastroenterology and nutrition,
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
January 1988,
Clinical therapeutics,
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
May 1992,
The American journal of gastroenterology,
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
January 1993,
La Pediatria medica e chirurgica : Medical and surgical pediatrics,
G Iacono, and
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G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
April 2001,
Pediatrics,
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
January 1998,
Journal of investigational allergology & clinical immunology,
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
June 1990,
Anales espanoles de pediatria,
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
December 1993,
Clinical pharmacy,
G Iacono, and
A Carroccio, and
G Montalto, and
F Cavataio, and
D Lorello, and
M Soresi, and
I Kazmierska, and
V Balsamo
February 2000,
The American journal of gastroenterology,
