Placental transfer of cadmium. 1992

B J Lagerkvist, and G F Nordberg, and H A Söderberg, and S Ekesrydh, and V Englyst, and M Gustavsson, and N O Gustavsson, and D E Wiklund
Department of Environmental Medicine, Umeå University, Sweden.

Cadmium levels in blood have been determined in mother-newborn pairs from the surroundings of a copper smelter and a control area in Northern Sweden. The smelter's cadmium emissions to the air have decreased substantially since the 1970s, and in 1989 the emission was one ton. Venous blood was sampled from the mothers during delivery and from the umbilical cords, and analysed for cadmium by flameless atomic absorption spectrophotometry. There were no significant differences in cadmium levels, as between exposed women and controls, and blood levels were low, even in an industrial area. The most important environmental exposure seemed to be smoking. There was, however, a significant increase in cadmium levels during pregnancy among non-smoking women in both groups, p < 0.01. The cadmium levels in the newborn babies were about 70% of those in the mothers. Cadmium levels in the babies of non-smoking mothers were significantly higher in the vicinity of the smelter than in the control area (p < 0.05).

UI MeSH Term Description Entries
D007221 Industry Any enterprise centered on the processing, assembly, production, or marketing of a line of products, services, commodities, or merchandise, in a particular field often named after its principal product. Examples include the automobile, fishing, music, publishing, insurance, and textile industries. Tertiary Sector,Industries,Sector, Tertiary,Sectors, Tertiary,Tertiary Sectors
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007854 Lead A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb.
D008431 Maternal-Fetal Exchange Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission. Transplacental Exposure,Exchange, Maternal-Fetal,Exposure, Transplacental,Maternal Fetal Exchange
D010920 Placenta A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES). Placentoma, Normal,Placentome,Placentas,Placentomes
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011248 Pregnancy Complications Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases. Adverse Birth Outcomes,Complications, Pregnancy,Adverse Birth Outcome,Birth Outcome, Adverse,Complication, Pregnancy,Outcome, Adverse Birth,Pregnancy Complication
D002104 Cadmium An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
D003300 Copper A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. Copper-63,Copper 63
D004781 Environmental Exposure The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals. Exposure, Environmental,Environmental Exposures,Exposures, Environmental

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