-transparent.png){kind=logo}
Absolute linkage between the gene, on chromosome 19, for the calcium release channel (CRC) of the sarcoplasmic reticulum in skeletal muscle and malignant hyperthermia (MH) has been reported by other workers. In the present study of three Swedish Families informative with respect to this linkage relationship, definite recombinants were found in two families. We conclude that mutations in other genes than the CRC gene can cause the clinical picture of MH. Accordingly, MH appears to be genetically heterogeneous.
Related Publications
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
March 1993,
Biochemistry and molecular biology international,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
January 1987,
Veterinary research communications,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
December 1993,
Annals of the New York Academy of Sciences,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
September 1992,
Anesthesia and analgesia,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
January 2002,
Journal of anesthesia,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
July 1986,
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
September 2001,
Anesthesiology,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
November 1998,
Biophysical journal,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
April 1992,
Anesthesiology,
T Fagerlund, and
G Islander, and
E Ranklev, and
I Harbitz, and
J G Hauge, and
E Møkleby, and
K Berg
February 1989,
The American journal of physiology,
