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The isolation of pregnane-3 omega, 11 beta, 21-triol-20-one, allopregnane-3 omega, 11 beta, 21-triol-20-one, pregnane-3 omega, 21-diol-11,20-dione and delta 4-pregnene-11 beta, 21-diol-3,20-dione from the urine or normal subjects treated with corticotropin. 1954

J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN

UI MeSH Term Description Entries
D011278 Pregnanes Saturated derivatives of the steroid pregnane. The 5-beta series includes PROGESTERONE and related hormones; the 5-alpha series includes forms generally excreted in the urine.
D011283 Pregnenes Unsaturated derivatives of PREGNANES.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000324 Adrenocorticotropic Hormone An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP). ACTH,Adrenocorticotropin,Corticotropin,1-39 ACTH,ACTH (1-39),Adrenocorticotrophic Hormone,Corticotrophin,Corticotrophin (1-39),Corticotropin (1-39),Hormone, Adrenocorticotrophic,Hormone, Adrenocorticotropic
D013256 Steroids A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed) Steroid,Catatoxic Steroids,Steroids, Catatoxic
D014556 Urine Liquid by-product of excretion produced in the kidneys, temporarily stored in the bladder until discharge through the URETHRA.

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J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
The C-11-beta-hydroxylation of delta 4-pregnene-6 beta,17 alpha,21-triol-3,20-dione.
May 1954, Archives of biochemistry and biophysics,
J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
The isolation of delta 4-pregnene-11 beta, 17 alpha, 20 alpha, 21-tetrol-3-one and delta 4-pregnene-11 beta,17 alpha,20 beta, 21-tetrol-3-one from human adrenal incubates.
April 1959, The Journal of clinical endocrinology and metabolism,
J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
Isolation of delta 4-pregnene-11 beta, 17 alpha, 20 alpha, 21-tetrol-3-one from urine of man.
August 1957, Archives of biochemistry and biophysics,
J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
Partial synthesis of pregnene-4-triol-17(beta), 20(beta), 21-dione-3,11 and pregnene-4-diol-17(beta), 21-trione-3,11,20 monoacetate.
March 1946, The Journal of biological chemistry,
J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
Identification of delta 4-pregnene-11 beta, 21-triol-3-one in urine extract after administration of 11-dehydrocorticosterone acetate.
June 1958, The Journal of clinical endocrinology and metabolism,
J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
Isolation of delta 1, 4-pregnadiene-3-20-dione-11beta-17alpha-21-triol from the urine of patients treated with metacortandracin.
January 1956, The Journal of clinical endocrinology and metabolism,
J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
Characterization of the 21-yl sulfates of 11-beta, 17-alpha,21-trihydroxypregn-4-ene-3,20-dione; 17-alpha,21-dihydroxypregn-4-ene-3, 11,20-trione; 11-beta,21-dihydroxyregn-4-ene-3,20-dione; 21-hydroxypregn-4-ene-3, 11,20-trione and 21-hydroxypregn-4-ene,3,20-dione in human cord plasma.
August 1969, Steroids,
J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
Isolation and identification of 3-alpha,21-dihydroxy-5-alpha-pregnane-11,20-dione from urine.
July 1965, Analytical biochemistry,
J C TOUCHSTONE, and H BULASCHENKO, and E M RICHARDSON, and F C DOHAN
[A new endogenous steroid: isolation of delta 4-pregnene-11 beta, 17 alpha, 20 alpha, 21-tetraol-3-one].
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[Microbial transformation of 16 alpha-methyl-5 alpha-delta 9(11)- pregnene-3 beta, 17 alpha, 21-triol-20-one-3 beta, 21-diacetate].
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