BIOMAT Database Logo BIOMAT Database Logo

Gas chromatographic-mass spectrometric methods of analysis for detection of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in biological matrices. 1992

W E Bronner, and A S Xu
Armed Forces Institute of Pathology, Division of Forensic Toxicology, Washington, DC 20306-6000.

Gas chromatographic-mass spectrometric methods of analysis for the detection of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid, a major metabolite of delta 9-tetrahydrocannabinol, are reviewed. Emphasis is on analytical methodology including numerous derivatization techniques developed specifically for this analyte. The majority of procedures cited in the literature were developed to detect this metabolite in the blood and urine of man.

UI MeSH Term Description Entries
D008401 Gas Chromatography-Mass Spectrometry A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds. Chromatography, Gas-Liquid-Mass Spectrometry,Chromatography, Gas-Mass Spectrometry,GCMS,Spectrometry, Mass-Gas Chromatography,Spectrum Analysis, Mass-Gas Chromatography,Gas-Liquid Chromatography-Mass Spectrometry,Mass Spectrometry-Gas Chromatography,Chromatography, Gas Liquid Mass Spectrometry,Chromatography, Gas Mass Spectrometry,Chromatography, Mass Spectrometry-Gas,Chromatography-Mass Spectrometry, Gas,Chromatography-Mass Spectrometry, Gas-Liquid,Gas Chromatography Mass Spectrometry,Gas Liquid Chromatography Mass Spectrometry,Mass Spectrometry Gas Chromatography,Spectrometries, Mass-Gas Chromatography,Spectrometry, Gas Chromatography-Mass,Spectrometry, Gas-Liquid Chromatography-Mass,Spectrometry, Mass Gas Chromatography,Spectrometry-Gas Chromatography, Mass,Spectrum Analysis, Mass Gas Chromatography
D009626 Terminology as Topic Works about the terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area. Etymology,Nomenclature as Topic,Etymologies
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013759 Dronabinol A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound. THC,Tetrahydrocannabinol,delta(9)-THC,9-ene-Tetrahydrocannabinol,Marinol,Tetrahydrocannabinol, (6a-trans)-Isomer,Tetrahydrocannabinol, (6aR-cis)-Isomer,Tetrahydrocannabinol, (6aS-cis)-Isomer,Tetrahydrocannabinol, Trans-(+-)-Isomer,Tetrahydrocannabinol, Trans-Isomer,delta(1)-THC,delta(1)-Tetrahydrocannabinol,delta(9)-Tetrahydrocannabinol,9 ene Tetrahydrocannabinol,Tetrahydrocannabinol, Trans Isomer
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular

Related Publications

W E Bronner, and A S Xu
Thin-layer chromatographic-mass spectrometric identification of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid.
July 1983, Journal of chromatography,
W E Bronner, and A S Xu
Gas chromatographic-mass spectrometric quantitation of urinary 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid after derivatization by direct extractive alkylation.
August 1993, Journal of chromatography,
W E Bronner, and A S Xu
Solid-phase extraction of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid from human urine with gas chromatographic-mass spectrometric confirmation.
June 1991, Journal of chromatography,
W E Bronner, and A S Xu
A sensitive thin-layer chromatographic procedure for the detection of urinary 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid.
January 1988, Journal of analytical toxicology,
W E Bronner, and A S Xu
Synthesis of optically active (-)-11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid.
November 1991, Pharmacology, biochemistry, and behavior,
W E Bronner, and A S Xu
Gas chromatography-mass spectrometry-single ion monitoring measurement of 11-nor-delta 9-tetrahydrocannabinol-carboxylic acid in urine.
April 2003, Journal of chromatographic science,
W E Bronner, and A S Xu
Semi-quantitative thin-layer mass-screening detection of 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in human urine.
March 1982, Journal of chromatography,
W E Bronner, and A S Xu
[Detection of 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid in urine using thin-layer chromatography].
February 1997, Soudni lekarstvi,
W E Bronner, and A S Xu
Detection and quantitation of urinary 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid, a metabolite of tetrahydrocannabinol, by capillary gas chromatography and electron impact mass fragmentography.
January 1987, Journal of analytical toxicology,
W E Bronner, and A S Xu
A rapid sample-preparation technique for thin-layer chromatographic analysis for 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in human urine.
January 1989, Clinical chemistry,
Copied contents to your clipboard!