-transparent.png){kind=logo}
This study discusses four children of hepatocellular carcinoma (HCC) who were asymptomatic HBsAg carriers or had HBsAg-positive chronic hepatitis for 3 to 11 years before the occurrence of the carcinoma. Three of these four patients were positive for anti-HBe at 3 to 5 years before the diagnosis of hepatocellular carcinoma. Autopsy findings disclosed liver cirrhosis in all the four patients. To the best of our knowledge few reports have documented children in HBsAg carrier status or with HBsAg-positive hepatitis prior to the development of hepatocellular carcinoma. It is emphasized that HBsAg-positive children, with or without detectable hepatic lesions in routine examinations, have a possibility of developing HCC, and should be carefully monitored for long periods.
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
July 1985,
Japanese journal of cancer research : Gann,
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
November 1983,
Acta pathologica japonica,
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
January 1982,
Indian journal of cancer,
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
October 1992,
Gastroenterology,
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
September 1985,
American journal of diseases of children (1960),
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
September 2009,
Journal of medical virology,
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
December 1979,
Virchows Archiv. A, Pathological anatomy and histology,
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
January 1978,
Gastroenterology,
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
January 1995,
Princess Takamatsu symposia,
Y Tazawa, and
F Nishinomiya, and
H Noguchi, and
S Tsuchiya, and
Y Hayashi, and
D Abukawa, and
M Watabe, and
M Nakagawa, and
M Imaizumi, and
R Ohi
May 2017,
Alimentary pharmacology & therapeutics,
