BIOMAT Database Logo BIOMAT Database Logo

Total sympathetic activity and atrial natriuretic factor levels in VVI and DDD pacing with different atrioventricular delays during daily activity and exercise. 1992

G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Cardiac Department of Athens General Hospital, Athens University, Greece.

The purpose of the study was to assess at rest and during exercise total sympathetic activity, as expressed by plasma cyclic AMP (cAMP) blood levels and sinus node activity (SNA), as well as atrial natriuretic factor (ANF) blood levels in VVI and DDD pacing with long and short atrioventricular delays in DDD paced patients suffering from complete heart block. Clinical parameters, such as exercise time, and arterial blood pressure (ABP) were also taken into consideration. Thirteen patients (six males, mean age 65 +/- 2 years), were examined randomly in VVI and DDD pacing with 100 and 150 ms atrioventricular delays (AVD). Plasma cAMP and ANF were measured at rest, at peak exercise and 15 and 30 min after the test. The cAMP at rest remained unchanged whatever the pacing mode or the AVD, but 30 min after exercise, the cAMP levels were statistically lower in DDD pacing with short AVD (100 ms) than in DDD with long AVD (150 ms) or VVI pacing (cAMP DDD/100 ms: 16 +/- 0.8 pmol.ml-1, cAMP DDD/150 ms: 20 +/- 2 pmol.ml-1, P < 0.01, cAMP VVI: 29 pmol.ml-1, P < 0.001). ANF plasma levels at rest were significantly higher in VVI pacing than in DDD modes, with either long or short AVD (ANF DDD/100 ms: 93 +/- 10 pg.ml-1, ANF DDD/150 ms: 100 +/- 13 pg.ml-1, ANF VVI: 150 +/- 16 pg.ml-1, P < 0.001, P < 0.03 respectively compared to VVI).(ABSTRACT TRUNCATED AT 250 WORDS)

UI MeSH Term Description Entries
D008297 Male Males
D009320 Atrial Natriuretic Factor A potent natriuretic and vasodilatory peptide or mixture of different-sized low molecular weight PEPTIDES derived from a common precursor and secreted mainly by the HEART ATRIUM. All these peptides share a sequence of about 20 AMINO ACIDS. ANF,ANP,Atrial Natriuretic Peptide,Atrial Natriuretic Peptides,Atriopeptins,Auriculin,Natriuretic Peptides, Atrial,ANF (1-126),ANF (1-28),ANF (99-126),ANF Precursors,ANP (1-126),ANP (1-28),ANP Prohormone (99-126),ANP-(99-126),Atrial Natriuretic Factor (1-126),Atrial Natriuretic Factor (1-28),Atrial Natriuretic Factor (99-126),Atrial Natriuretic Factor Precursors,Atrial Natriuretic Factor Prohormone,Atrial Natriuretic Peptide (1-126),Atrial Pronatriodilatin,Atriopeptigen,Atriopeptin (1-28),Atriopeptin (99-126),Atriopeptin 126,Atriopeptin Prohormone (1-126),Cardiodilatin (99-126),Cardiodilatin Precursor,Cardionatrin I,Cardionatrin IV,Prepro-ANP,Prepro-CDD-ANF,Prepro-Cardiodilatin-Atrial Natriuretic Factor,Pro-ANF,ProANF,Proatrial Natriuretic Factor,Pronatriodilatin,alpha ANP,alpha-ANP Dimer,alpha-Atrial Natriuretic Peptide,beta-ANP,beta-Atrial Natriuretic Peptide,gamma ANP (99-126),gamma-Atrial Natriuretic Peptide,Natriuretic Peptide, Atrial,Peptide, Atrial Natriuretic,Peptides, Atrial Natriuretic,Prepro ANP,Prepro CDD ANF,Prepro Cardiodilatin Atrial Natriuretic Factor,Pro ANF,alpha ANP Dimer,alpha Atrial Natriuretic Peptide,beta ANP,beta Atrial Natriuretic Peptide,gamma Atrial Natriuretic Peptide
D010138 Pacemaker, Artificial A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external). Cardiac Pacemaker, Artificial,Artificial Cardiac Pacemaker,Artificial Cardiac Pacemakers,Artificial Pacemaker,Artificial Pacemakers,Cardiac Pacemakers, Artificial,Pacemaker, Artificial Cardiac,Pacemakers, Artificial,Pacemakers, Artificial Cardiac
D002304 Cardiac Pacing, Artificial Regulation of the rate of contraction of the heart muscles by an artificial pacemaker. Pacing, Cardiac, Artificial,Artificial Cardiac Pacing,Artificial Cardiac Pacings,Cardiac Pacings, Artificial,Pacing, Artificial Cardiac,Pacings, Artificial Cardiac
D005260 Female Females
D006327 Heart Block Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects. Auriculo-Ventricular Dissociation,A-V Dissociation,Atrioventricular Dissociation,A V Dissociation,A-V Dissociations,Atrioventricular Dissociations,Auriculo Ventricular Dissociation,Auriculo-Ventricular Dissociations,Block, Heart,Blocks, Heart,Dissociation, A-V,Dissociation, Atrioventricular,Dissociation, Auriculo-Ventricular,Dissociations, A-V,Dissociations, Atrioventricular,Dissociations, Auriculo-Ventricular,Heart Blocks
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000203 Activities of Daily Living The performance of the basic activities of self care, such as dressing, ambulation, or eating. ADL,Chronic Limitation of Activity,Limitation of Activity, Chronic,Activities, Daily Living,Activity, Daily Living,Daily Living Activities,Daily Living Activity,Living Activities, Daily,Living Activity, Daily
D000242 Cyclic AMP An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. Adenosine Cyclic 3',5'-Monophosphate,Adenosine Cyclic 3,5 Monophosphate,Adenosine Cyclic Monophosphate,Adenosine Cyclic-3',5'-Monophosphate,Cyclic AMP, (R)-Isomer,Cyclic AMP, Disodium Salt,Cyclic AMP, Monoammonium Salt,Cyclic AMP, Monopotassium Salt,Cyclic AMP, Monosodium Salt,Cyclic AMP, Sodium Salt,3',5'-Monophosphate, Adenosine Cyclic,AMP, Cyclic,Adenosine Cyclic 3',5' Monophosphate,Cyclic 3',5'-Monophosphate, Adenosine,Cyclic Monophosphate, Adenosine,Cyclic-3',5'-Monophosphate, Adenosine,Monophosphate, Adenosine Cyclic
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

Related Publications

G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Sympathetic nerve activity during VVI and DDD pacing.
May 1989, Pacing and clinical electrophysiology : PACE,
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Twenty four hour variation in plasma atrial natriuretic factor during VVI and DDD pacing.
June 1996, Heart (British Cardiac Society),
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Left atrial appendage function during DDD and VVI pacing.
May 1997, Heart (British Cardiac Society),
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Higher sympathetic nerve activity during ventricular (VVI) than during dual-chamber (DDD) pacing.
December 1996, Journal of the American College of Cardiology,
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Atrial natriuretic factor release during exercise in patients successively paced in DDD and rate matched ventricular pacing.
April 1992, Pacing and clinical electrophysiology : PACE,
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Effects of ventricular pacing on atrial natriuretic peptide levels during submaximal exercise in complete atrioventricular block.
June 1990, The American journal of cardiology,
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Is DDD pacing superior to VVI,R? A study on cardiac sympathetic nerve activity and myocardial oxygen consumption at rest and during exercise.
April 1992, Pacing and clinical electrophysiology : PACE,
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Comparison of DDD and 'VVI-R like' pacing during moderate exercise: echo-Doppler study.
July 1992, European heart journal,
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
[Evaluation of maintenance of cardiac output during DDD and VVI pacing by exercise Doppler echocardiography].
January 1991, Journal of cardiology,
G N Theodorakis, and D T Kremastinos, and M Markianos, and E Livanis, and G Karavolias, and P K Toutouzas
Effect of different AV delays on left ventricular diastolic function and ANF levels in DDD paced hypertensive patients during daily activity and exercise.
April 1999, Pacing and clinical electrophysiology : PACE,
Copied contents to your clipboard!