-transparent.png){kind=logo}
We used the taste reactivity (TR) test, a direct measure of the hedonic properties of a tastant, to assess in Sprague-Dawley rats the ability of morphine (an opiate agonist) and naltrexone (an opiate antagonist) to modify the palatability of a bitter quinine solution and a sweet sucrose solution. Morphine reduced the aversive hedonic properties of both novel and familiar quinine solution (0.05% and 0.1%) but did not modify the palatability of 20% sucrose solution. Naltrexone reduced the positive hedonic properties of sucrose solution (2% and 20%) but did not modify the palatability of 0.05% quinine solution. The pattern of results suggests that the modification of feeding produced by opiate agonists and antagonists may be mediated by an hedonic shift in the palatability of the tastant.
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
August 1994,
Pharmacology, biochemistry, and behavior,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
March 1994,
Pharmacology, biochemistry, and behavior,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
March 1996,
Pharmacology, biochemistry, and behavior,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
January 1995,
Neuroscience and biobehavioral reviews,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
March 1992,
Pharmacology, biochemistry, and behavior,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
November 2005,
Physiology & behavior,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
January 1995,
Pharmacology, biochemistry, and behavior,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
October 2016,
Psychopharmacology,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
February 2007,
Physiology & behavior,
L A Parker, and
S Maier, and
M Rennie, and
J Crebolder
November 1993,
Pharmacology, biochemistry, and behavior,
