Biomaterial Database

[Long-term results of small cell lung cancer treated by surgical resection and multimodality therapy]. 1992

J Z Xu

Thoracic Tumor Institute and Hospital, Bei jing.

241 patients with small cell lung cancer (SCLC) were operated in our hospital from 1957 to 1985. The early postoperative mortality was 1.7%. The 5-yr survival rate was 23.2% (56/241). The 10-yr survival rate was 16.5% (15/91) (only 4 patients died during 5-yr to 10-yr after surgery but none of them died of SCLC). We analysed the 5-yr survival group. The 5-yr survival rate for stage I patients was 52.3% (23/44), stage II 34.1% (14/41), stage III 12.8% (19/149) [IIIa12.3% (17/138),IIIb 18.2% (2/11)]. Stage IV 0 (0/3). The P value: I vs IIIaP < 0.001, II vs IIIaP < 0.01. 125 patients received chemotherapy (CT) and/or radiotherapy (RT) postoperatively (group A) and the other 112 cases received surgical resection only (group B). 4 patients (3 IIIa, 1 IIIb) who died in early postoperative period were not counted. The 5-yr survival rate for group A and B was 40.8% (51/125) and 4.5% (5/112) respectively, P < 0.001; for group A and B stage I was 71.4% (20/28) and 18.8% (3/16), P < 0.01;for group A and B stage II was 54.5% (12/22) and 10.5% (2/19), P < 0.01; for group A and B stage IIIa was 25.4% (17/67) and 0 (0/71), P < 0.001. There were no differences in 5-yr survival rate on types of surgical resection and locations of the disease. The present results revealed that the total 5-yr survival rate for SCLC was 23.2%, among them for resection only was 4.5% and for resection plus multimodality therapy was 40.8%.(ABSTRACT TRUNCATED AT 250 WORDS)

UI	MeSH Term	Description	Entries
D008175	Lung Neoplasms	Tumors or cancer of the LUNG.	Cancer of Lung,Lung Cancer,Pulmonary Cancer,Pulmonary Neoplasms,Cancer of the Lung,Neoplasms, Lung,Neoplasms, Pulmonary,Cancer, Lung,Cancer, Pulmonary,Cancers, Lung,Cancers, Pulmonary,Lung Cancers,Lung Neoplasm,Neoplasm, Lung,Neoplasm, Pulmonary,Pulmonary Cancers,Pulmonary Neoplasm
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009367	Neoplasm Staging	Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.	Cancer Staging,Staging, Neoplasm,Tumor Staging,TNM Classification,TNM Staging,TNM Staging System,Classification, TNM,Classifications, TNM,Staging System, TNM,Staging Systems, TNM,Staging, Cancer,Staging, TNM,Staging, Tumor,System, TNM Staging,Systems, TNM Staging,TNM Classifications,TNM Staging Systems
D003131	Combined Modality Therapy	The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.	Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly