[Experimental study of the trophic effects of reinnervation of pedicled muscle flaps]. 1992

G Dautel, and J Braga da Silva, and J Floquet, and M Merle
Service de Chirurgie D, Hôpital Jeanne-d'Arc, Dommartin-les-Toul.

Any transplanted muscle flap undergoes atrophy to an extent depending mainly on its innervation. Other factors such as the tension at rest and the duration of ischemia play a secondary role. An experimental study was carried out in rats to quantitatively assess the extent of atrophy according to the mode of transplant reinnervation. The gracilis muscle was used as an experimental model of pedicled flap after verifying the axial nature of its vasculature. Results were assessed after three months from a histological point of view and in terms of postoperative weight in four different groups of 13 rats. The first three groups reproduced situation encountered in clinic: intact nerve, sutured nerve, resected nerve. A graft sensory neurotization technique was implemented in the fourth group by diverting a neighboring sensory nerve. The best trophic results were obtained when the motor nerve remained continuous. The sensory neurotization technique did not significantly influence the trophic evolution after three months.

UI MeSH Term Description Entries
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D011184 Postoperative Period The period following a surgical operation. Period, Postoperative,Periods, Postoperative,Postoperative Periods
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001284 Atrophy Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. Atrophies
D013524 Surgical Flaps Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region. Island Flap,Island Flaps,Flap, Surgical,Flaps, Surgical,Pedicled Flap,Surgical Flap,Flap, Island,Flap, Pedicled,Flaps, Island,Flaps, Pedicled,Pedicled Flaps
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

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