Three HLA-D region antigens defined by primed LD typing. 1976

F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach

We have recently described a new method, primed LD typing or PLT, for specific identification of HLA-D antigens. Highly discriminatory PLT cells have been developed which clearly differentiate between cells of individuals that restimulate strongly and those that restimulate weakly. Seven such discriminatory PLT cells have been used to define three antigens called PL1, PL2, and PL3; two more PLT cells may define antigen(s) PL4.

UI MeSH Term Description Entries
D007959 Lymphocyte Culture Test, Mixed Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens. Leukocyte Culture Test, Mixed,Mixed Lymphocyte Culture Test,Mixed Lymphocyte Reaction,Mixed Leukocyte Culture Test,Mixed Leukocyte Reaction,Leukocyte Reaction, Mixed,Leukocyte Reactions, Mixed,Lymphocyte Reaction, Mixed,Lymphocyte Reactions, Mixed,Mixed Leukocyte Reactions,Mixed Lymphocyte Reactions
D005796 Genes A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms. Cistron,Gene,Genetic Materials,Cistrons,Genetic Material,Material, Genetic,Materials, Genetic
D006649 Histocompatibility Antigens A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection. Transplantation Antigens,Antigens, Transplantation,Histocompatibility Antigen,LD Antigens,SD Antigens,Antigen, Histocompatibility,Antigens, Histocompatibility,Antigens, LD,Antigens, SD
D006680 HLA Antigens Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases. Human Leukocyte Antigen,Human Leukocyte Antigens,Leukocyte Antigens,HL-A Antigens,Antigen, Human Leukocyte,Antigens, HL-A,Antigens, HLA,Antigens, Human Leukocyte,Antigens, Leukocyte,HL A Antigens,Leukocyte Antigen, Human,Leukocyte Antigens, Human
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
September 1976, Transplantation proceedings,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
March 1977, Transplantation proceedings,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
August 1976, Tissue antigens,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
January 1977, Scandinavian journal of immunology,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
January 1981, Tissue antigens,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
December 1978, Transplantation proceedings,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
October 1977, Tissue antigens,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
July 1981, Human immunology,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
December 1977, Transplantation proceedings,
F H Bach, and E Jarrett-Toth, and C J Benike, and M J Sheehy, and P M Sondel, and M L Bach
January 1981, Tissue antigens,
Copied contents to your clipboard!