The course of the disease is evaluated in 51 patients (21 children, 30 adults). Surgical removal was considered as the method of choice. Other methods did not improve the results. During the last years the number of adult patients with this disease has been increasing in our clinic. 50% of the adults and 25% of the children required only one surgical procedure. If the papillomas began in infancy the course of the disease was difficult and the number of recurrences very high. 61% of all patients kept a chronic hoarseness. A decisive turn of the therapy did not occur during the last years, even though the therapeutic risk has been diminished due to microsurgery and the intervals between the operations could be increased. According to other authors, ultrasound or CO2- Laser appear to shorten the length of the disease in some cases.