[Melanoma of the ORL mucosa]. 1992

J Mané, and D Stoll, and M M Delaunay, and L Traissac
C.H.U. Pellegrin Tripode, Clinique ORL, Bordeaux, France.

The study of ENT mucous melanomas (ENT MM) was performed retrospectively, based on 20 patients treated in Bordeaux and 156 detailed files taken from the international literature. Each paragraph is followed by a review of the general literature. The ENT MM, a rare form of melanomas, presents a majority of nasal locations. The mean age is 63 years old. The sex ratio trend is towards one. The aspecific call signs partially explain the delayed diagnosis. The difficult pathological examination is assisted by tumoral markers. Mean survival is two and a half years without any clear prognostic factors as for cutaneous melanomas. Treatment is essentially surgical, but adjuvant radiotherapy may have a significant effect. The other treatments are palliative.

UI MeSH Term Description Entries
D007820 Laryngeal Mucosa The mucous lining of the LARYNX, consisting of various types of epithelial cells ranging from stratified squamous EPITHELIUM in the upper larynx to ciliated columnar epithelium in the rest of the larynx, mucous GOBLET CELLS, and glands containing both mucous and serous cells. Laryngeal Epithelium,Epithelium, Laryngeal,Mucosa, Laryngeal
D008297 Male Males
D008545 Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) Malignant Melanoma,Malignant Melanomas,Melanoma, Malignant,Melanomas,Melanomas, Malignant
D009297 Nasal Mucosa The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells. Nasal Epithelium,Schneiderian Membrane,Epithelium, Nasal,Membrane, Schneiderian,Mucosa, Nasal
D010039 Otorhinolaryngologic Neoplasms A general concept for tumors or cancer of any part of the EAR; the NOSE; the THROAT; and the PHARYNX. It is used when there is no specific heading. Neoplasms, Otorhinolaryngologic,Neoplasms, Otorhinolaryngological,Ootorhinolaryngeal Neoplasms,Otorhinolaryngeal Cancer,Otorhinolaryngologic Neoplasm,Otorhinolaryngological Neoplasms,Cancer, Otorhinolaryngeal,Cancers, Otorhinolaryngeal,Neoplasm, Ootorhinolaryngeal,Neoplasm, Otorhinolaryngologic,Neoplasm, Otorhinolaryngological,Neoplasms, Ootorhinolaryngeal,Ootorhinolaryngeal Neoplasm,Otorhinolaryngeal Cancers,Otorhinolaryngological Neoplasm
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D003131 Combined Modality Therapy The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used. Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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