[A comparison of 3 single-dose plans for mebendazole in the treatment of trichuriasis]. 1992

E Ramírez Fernández, and L Miquet Romero, and C Finlay
Instituto de Medicina Tropical Pedro Kourí.

People infected by Trichuris trichiura were selected in a community by the Kato-Katz technique. The study included a universe of 376 persons, male and female, positive and asymptomatic, monoparasitic and multiparasitic. They were divided in treatment groups with not less than 50 people. Monoparasitic patients were treated with 500, 400 and 300 mg of mebendazole, and multiparasitic patients with 500 and 400 mg of mebendazole. In all the cases the drug was used in single doses and its administration was supervised by the physician. Therapeutical response in monoparasitic and multiparasitic patients is shown. It is suggested to use mebendazole single doses of 300 mg in monoparasitic and of 400 mg in multiparasitic patients with an intensiveness of less than 5,000 h/g, as an alternative for treating asymptomatic populations with T. trichiura.

UI MeSH Term Description Entries
D008297 Male Males
D008463 Mebendazole A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES. Anti-Worm,Bantenol,Banworm,Boots Threadworm Treatment,Lomper,Madicure,Mebendan,Mebenvet,Pripsen Mebendazole,R17635,Sqworm,Sufil,Surfont,Telmin,Vermicol,Vermidil,Vermox,Wormkuur,Anti Worm
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D012074 Remission Induction Therapeutic act or process that initiates a response to a complete or partial remission level. Induction of Remission,Induction, Remission,Inductions, Remission,Remission Inductions
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D004341 Drug Evaluation Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals. Evaluation Studies, Drug,Drug Evaluation Studies,Drug Evaluation Study,Drug Evaluations,Evaluation Study, Drug,Evaluation, Drug,Evaluations, Drug,Studies, Drug Evaluation,Study, Drug Evaluation
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

Related Publications

E Ramírez Fernández, and L Miquet Romero, and C Finlay
May 1979, The Medical journal of Australia,
E Ramírez Fernández, and L Miquet Romero, and C Finlay
January 1975, Wiadomosci parazytologiczne,
E Ramírez Fernández, and L Miquet Romero, and C Finlay
March 1975, The Journal of pediatrics,
E Ramírez Fernández, and L Miquet Romero, and C Finlay
May 1974, The American journal of tropical medicine and hygiene,
E Ramírez Fernández, and L Miquet Romero, and C Finlay
December 1975, Current therapeutic research, clinical and experimental,
E Ramírez Fernández, and L Miquet Romero, and C Finlay
August 1980, Indian pediatrics,
E Ramírez Fernández, and L Miquet Romero, and C Finlay
March 1977, The American journal of tropical medicine and hygiene,
E Ramírez Fernández, and L Miquet Romero, and C Finlay
December 1974, JAMA,
E Ramírez Fernández, and L Miquet Romero, and C Finlay
January 1975, Southern medical journal,
Copied contents to your clipboard!